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Volume 11 Supplement 1

5th International Conference on cGMP: Generators, Effectors and Therapeutic Implications

Meeting abstracts

5th International Conference on cGMP: Generators, Effectors and Therapeutic Implications

Halle, Germany

24-26 June 2011

Edited by John Burnett Jr, Franz Hofmann, Harald HHW Schmidt and Johannes-Peter Stasch

Conference website

Oral presentation   Open Access

Designer natriuretic peptides for heart failure: advanced in clinical development

John Burnett BMC Pharmacology 2011, 11(Suppl 1):O1 (1 August 2011)

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Oral presentation   Open Access

New clinical results with sGC stimulators

Jürgen Behr BMC Pharmacology 2011, 11(Suppl 1):O2 (1 August 2011)

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Oral presentation   Open Access Highly Accessed

LCZ696, an angiotensin receptor neprilysin inhibitor (ARNI): clinical development in heart failure and hypertension

Martin P Lefkowitz BMC Pharmacology 2011, 11(Suppl 1):O3 (1 August 2011)

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Biomarkers in kidney and heart disease

Alan S Maisel BMC Pharmacology 2011, 11(Suppl 1):O4 (1 August 2011)

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Human genetics, natriuretic peptides and hypertension

Christopher Newton-Cheh BMC Pharmacology 2011, 11(Suppl 1):O5 (1 August 2011)

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Benefits of PDE5 inhibition in patients with diastolic heart failure

Marco Guazzi BMC Pharmacology 2011, 11(Suppl 1):O6 (1 August 2011)

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Nitric oxide scavenging by red cell microparticles and cell free hemoglobin as a mechanism for hemolytic diseases and the red blood cell storage lesion

Marc T Gladwin BMC Pharmacology 2011, 11(Suppl 1):O7 (1 August 2011)

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Redox regulation of responses to hypoxia and NO-cGMP signaling in pulmonary vascular pathophysiology

Michael S Wolin, Boon Neo, Dhara Patel, Raed Alhawaj, Sharath Kandhi, Mansoor Ahmad BMC Pharmacology 2011, 11(Suppl 1):O8 (1 August 2011)

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Nitric oxide-independent stimulation of soluble guanylate cyclase attenuates pulmonary fibrosis

Oleg V Evgenov, Lin Zou, Ming Zhang, Mari Mino-Kenudson, Eugene J Mark, Emmanuel S Buys, Michael J Raher, Yan Li, Yan Feng, Rosemary C Jones, Johannes-Peter Stasch, Wei Chao BMC Pharmacology 2011, 11(Suppl 1):O9 (1 August 2011)

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Molecular aspects of sGC regulation

Michael A Marletta, Eric S Underbakke, Nathaniel B Fernhoff BMC Pharmacology 2011, 11(Suppl 1):O10 (1 August 2011)

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Structural insights into sGC activation by different activators

Focco van den Akker, Faye Martin, Vijay Kumar, Xiaolei Ma, Johannes-Peter Stasch, Martina Schaefer, Padmamalini Baskaran, Annie Beuve, Pete W van Dunten BMC Pharmacology 2011, 11(Suppl 1):O11 (1 August 2011)

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PKA: assembly of dynamic macromolecular signaling

Susan S Taylor, Ronit Ilouz, Manjula Darshi, Ganapathy Sarma, Alexandr Kornev, Ping Zhang BMC Pharmacology 2011, 11(Suppl 1):O12 (1 August 2011)

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Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication

Wolfgang R Dostmann, Brent W Osborne BMC Pharmacology 2011, 11(Suppl 1):O13 (1 August 2011)

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The crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding

Jeong Kim, Darren E Casteel, Gilbert Huang, Taek Kwon, Ronnie Ren, Peter Zwart, Jeffrey J Headd, Nicholas Brown, Dar-Chone Chow, Timothy Palzkill, Choel Kim BMC Pharmacology 2011, 11(Suppl 1):O14 (1 August 2011)

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Characterization of mice with a deletion of protein kinase G type I in cardiomyocytes and the effect on cardioprotection through either postconditioning or mitochondria-targeted S-nitrosothiol

Carmen Methner, Robert Lukowski, Franz Hofmann, Michael Murphy, Thomas Krieg BMC Pharmacology 2011, 11(Suppl 1):O15 (1 August 2011)

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Effects of long-term proBNP cardiac gene delivery in experimental hypertensive heart disease

Alessandro Cataliotti, Jason M Tonne, Guido Boerrigter, Salvatore Mangiafico, John C Burnett, Yasuhiro Ikeda BMC Pharmacology 2011, 11(Suppl 1):O16 (1 August 2011)

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Vascular and renal function of cGMP signalling

Jens Schlossmann, Elisabeth Schinner, Matthias Desch, Bernhard Hieke, Petra Rothammer, Katharina Salb, Andrea Schramm BMC Pharmacology 2011, 11(Suppl 1):O17 (1 August 2011)

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cGMP-PKG upregulates PGC1α and improves cardiac function in advanced cardiac hypertrophy independently of RGS2

Eiki Takimoto BMC Pharmacology 2011, 11(Suppl 1):O18 (1 August 2011)

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cGMP kinase I, cardiac hypertrophy and PDE inhibition

Enrico Patrucco, Robert Lukowski, Sergei Rybalkin, Joe Beavo, Franz Hofmann BMC Pharmacology 2011, 11(Suppl 1):O19 (1 August 2011)

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Molecular targets for PDE inhibitor-mediated improvement of cardiac dysfunction in the mdx mouse?

Candace M Adamo, Dao-Fu Dai, Justin M Percival, Elina Minami, Monte S Willis, Enrico Patrucco, Sergei D Rybalkin, Stanley C Froehner, Joseph A Beavo BMC Pharmacology 2011, 11(Suppl 1):O20 (1 August 2011)

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