BMC Pharmacology | Most Viewed

Advertisement

Articles

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
	26. 129 Accesses	Research article Computational models for in-vitro anti-tubercular activity of molecules based on high-throughput chemical biology screening datasets Vinita Periwal, Shireesha Kishtapuram, Open Source Drug Discovery Consortium, Vinod Scaria BMC Pharmacology 2012, 12:1 (31 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Computational methods based on Machine Learning tools and supervised classifiers generate accurate predictive models for virtual high-throughput screens of large libraries of anti-tubercular molecules, allowing prioritization of good candidates for drug discovery.
	27. 127 Accesses	Research article N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang BMC Pharmacology 2009, 9:7 (15 April 2009) Abstract \| Full text \| PDF \| PubMed
	28. 128 Accesses	Research article Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster John E Heidrich, Linda M Contos, Lucy A Hunsaker, Lorraine M Deck, David L Vander Jagt BMC Pharmacology 2004, 4:5 (19 April 2004) Abstract \| Full text \| PDF \| PubMed
	29. 127 Accesses	Research article Weight loss dynamics during combined fluoxetine and olanzapine treatment Jennifer A Perrone, Janet M Chabla, Brian H Hallas, Judith M Horowitz, German Torres BMC Pharmacology 2004, 4:27 (21 October 2004) Abstract \| Full text \| PDF \| PubMed
	30. 126 Accesses	Research article Effects of two atypical neuroleptics, olanzapine and risperidone, on the function of the urinary bladder and the external urethral sphincter in anesthetized rats Pedro L Vera, Alejandro Miranda-Sousa, Irving Nadelhaft BMC Pharmacology 2001, 1:4 (31 August 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	31. 125 Accesses	Research article Protective efficacy of natansnin, a dibenzoyl glycoside from Salvinia natans against CCl₄induced oxidative stress and cellular degeneration in rat liver Polimetla Srilaxmi, Gangadhara Sareddy, Polavarapu kishor, Oruganti Setty, Phanithi Babu BMC Pharmacology 2010, 10:13 (12 October 2010) Abstract \| Full text \| PDF \| PubMed
	32. 124 Accesses	Research article Quantitative in vitro and in vivo pharmacological profile of CE-178253, a potent and selective cannabinoid type 1 (CB₁) Receptor Antagonist John R Hadcock, Philip A Carpino, Philip A Iredale, Robert L Dow, Denise Gautreau, Lucinda Thiede, Dawn Kelly-Sullivan, Jeffrey S Lizano, Xingrong Liu, Jeffrey Van Deusen, Karen M Ward, Rebecca E O'Connor, Shawn C Black, David A Griffith, Dennis O Scott BMC Pharmacology 2010, 10:9 (16 August 2010) Abstract \| Full text \| PDF \| PubMed
	33. 125 Accesses	Research article Enhanced sensitivity to cisplatin and gemcitabine in Brca1-deficient murine mammary epithelial cells Elizabeth Alli, Vandana B Sharma, Anne-Renee Hartman, Patrick S Lin, Lisa McPherson, James M Ford BMC Pharmacology 2011, 11:7 (19 July 2011) Abstract \| Full text \| PDF \| PubMed
	34. 123 Accesses	Research article Antinociceptive effect of geranylgeraniol and 6α,7β-dihydroxyvouacapan-17β-oate methyl ester isolated from Pterodon pubescens Benth Humberto M Spindola, Leila Servat, Carina Denny, Rodney AF Rodrigues, Marcos N Eberlin, Elaine Cabral, Ilza MO Sousa, Jorge Y Tamashiro, João E Carvalho, Mary A Foglio BMC Pharmacology 2010, 10:1 (7 January 2010) Abstract \| Full text \| PDF \| PubMed
	35. 122 Accesses	Research article Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells Leilei Tang, Saskia M Bergevoet, Christian Gilissen, Theo de Witte, Joop H Jansen, Bert A van der Reijden, Reinier AP Raymakers BMC Pharmacology 2010, 10:12 (13 September 2010) Abstract \| Full text \| PDF \| PubMed
	36. 122 Accesses	Research article 5-hydroxytryptamine (5-HT) reduces total peripheral resistance during chronic infusion: direct arterial mesenteric relaxation is not involved Robert Davis, Jill Pattison, Janice M Thompson, Ruslan Tiniakov, Karie E Scrogin, Stephanie W Watts BMC Pharmacology 2012, 12:4 (6 May 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Chronic infusion with 5-hydroxytryptamine (5-HT) reduces total peripheral resistance, and this effect is not due to direct arterial mesenteric relaxation since 5-HT receptors present in the superior mesenteric artery are not functional.
	37. 122 Accesses	Software Pharmacological profiles of opioid ligands at Kappa opioid receptors Parham Gharagozlou, Ezzat Hashemi, Timothy M DeLorey, J David Clark, Jelveh Lameh BMC Pharmacology 2006, 6:3 (25 January 2006) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The activity of 15 opioid ligands at kappa-opioid receptors has been characterized by determining the extent of inhibition of forskolin-stimulated cAMP production in cells expressing only these receptors.
	38. 121 Accesses	Research article Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice Hossein Hosseinzadeh, Gholam_Reza Karimi, Maryam Ameri BMC Pharmacology 2002, 2:21 (19 December 2002) Abstract \| Full text \| PDF \| PubMed
	39. 120 Accesses	Hypothesis Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity? Matt T Bianchi, Emmanuel J Botzolakis BMC Pharmacology 2010, 10:3 (2 March 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Mapping the full drug-receptor interaction network may be critical for future drug discovery in neurological and psychiatric disorders as the clinical efficacy of an individual therapeutic agent is influenced by the ability to modulate multiple molecular targets.
	40. 120 Accesses	Database BIAdb: A curated database of benzylisoquinoline alkaloids Deepak Singla, Arun Sharma, Jasjit Kaur, Bharat Panwar, Gajendra PS Raghava BMC Pharmacology 2010, 10:4 (5 March 2010) Abstract \| Full text \| PDF \| PubMed
	41. 117 Accesses	Research article Seed germination, phenology, and antiedematogenic activity of Peperomia pellucida (L.) H. B. K. Maria Arrigoni-Blank, Ricardo Oliveira, Sandra Mendes, Paulo Silva, Ângelo Antoniolli, Jeane Vilar, Sócrates Cavalcanti, Arie Blank BMC Pharmacology 2002, 2:12 (9 May 2002) Abstract \| Full text \| PDF \| PubMed
	42. 116 Accesses	Research article Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A₃adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts Tina C Wan, Dilip K Tosh, Lili Du, Elizabeth T Gizewski, Kenneth A Jacobson, John A Auchampach BMC Pharmacology 2011, 11:11 (31 October 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A Polyamidoamine (PAMAM) dendrimer conjugated to 64 moieties of a nucleoside agonist binds to the mouse A3 adenosine receptor with enhanced potency and selectivity, and mediates cardioprotective effects in an isolated heart model of ischemia/reperfusion injury.
	43. 115 Accesses	Research article Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys Naveen Tirkey, Gaganjit Kaur, Garima Vij, Kanwaljit Chopra BMC Pharmacology 2005, 5:15 (15 October 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	44. 113 Accesses	Research article Salvianolic acid B functioned as a competitive inhibitor of matrix metalloproteinase-9 and efficiently prevented cardiac remodeling Baohong Jiang, Jing Chen, Lingling Xu, Zhenting Gao, Yanping Deng, Yanhui Wang, Feng Xu, Xu Shen, De-an Guo BMC Pharmacology 2010, 10:10 (25 August 2010) Abstract \| Full text \| PDF \| PubMed
	45. 113 Accesses	Research article Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells Lars H Jensen, Marielle Dejligbjerg, Lasse T Hansen, Morten Grauslund, Peter B Jensen, Maxwell Sehested BMC Pharmacology 2004, 4:31 (2 December 2004) Abstract \| Full text \| PDF \| PubMed
	46. 111 Accesses	Research article Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice Hossein Hosseinzadeh, Marjan Nassiri Asl BMC Pharmacology 2003, 3:3 (29 April 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	47. 110 Accesses	Research article Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA₁ receptor signalling in rat brain cryosections without affecting global LPA degradation Niina Aaltonen, Marko Lehtonen, Katri Varonen, Gemma Goterris, Jarmo T Laitinen BMC Pharmacology 2012, 12:7 (11 June 2012) Abstract \| Full text \| PDF \| PubMed
	48. 110 Accesses	Research article Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora BMC Pharmacology 2009, 9:8 (15 April 2009) Abstract \| Full text \| PDF \| PubMed
	49. 109 Accesses	Research article Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro W Dimpfel, JA Hoffmann BMC Pharmacology 2011, 11:2 (21 February 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The new Parkinson`s disease drug rasagiline and its metabolite aminoindan, affect the glutamate receptor mediated signaling pathway and display dose-dependent neuroprotective activity in the rat hippocampus.
	50. 108 Accesses	Research article Amphetamine Dependence and Co-Morbid Alcohol Abuse: Associations to Brain Cortical Thickness Glenn Lawyer, Petr S Bjerkan, Anders Hammarberg, Nitya Jayaram-Lindström, Johan Franck, Ingrid Agartz BMC Pharmacology 2010, 10:5 (20 May 2010) Abstract \| Full text \| PDF \| PubMed