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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good, PhD
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Molecular Biology 2009, 10 :55
RNF168, a recently identified RING finger protein, exhibits ubiquitin ligase activity which targets the H2A family of histones, and on genotoxic insult, colocalizes with H2AX at dsDNA breaks, activating prolonged ubiquitination and amplifying the DNA damage response.
BMC Molecular Biology 2009, 10 :51
Muscle-specific modifications of histones H3 and H4 within the Desmin gene cluster and its 5' locus control region correlate with different patterns of DNA methylation and gene expression in human myoblasts and myotubes but not blood cells.
BMC Molecular Biology 2009, 10 :38
Dicer and TAR RNA binding protein (TRBP), components of the human RNA-induced silencing complex (RISC), interact via specific domains and deletion of one of the domains, C4 of TRBP, prevents colocalization and RNA interference.
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Research article
Expression of HNF4alpha in the human and rat choroid plexus - Implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier Monika Niehof, Juergen Borlak BMC Molecular Biology 2009, 10 :68 (3 [Abstract ] [Provisional PDF ]
Research article
Cooperation between NRF-2 and YY-1 transcription factors is essential for triggering the expression of the PREPL-C2ORF34 bidirectional gene pair Chien-Chang Huang, Wun-Shaing W Chang BMC Molecular Biology 2009, 10 :67 (3 [Abstract ] [Provisional PDF ]
Research article
Identification of valid reference genes during the differentiation of human myoblasts Jens Stern-Straeter, Gabriel A Bonaterra, Karl Hormann, Ralf Kinscherf, Ulrich R Goessler BMC Molecular Biology 2009, 10 :66 (2 [Abstract ] [Provisional PDF ]
Research article
The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies Philippos A Papathanos, Nikolai Windbichler, Miriam Menichelli, Austin Burt, Andrea Crisanti BMC Molecular Biology 2009, 10 :65 (2 [Abstract ] [Provisional PDF ]
Research article
Identification of a novel nucleolin related protein (NRP) gene expressed during rat spermatogenesis
Keerthi T Chathoth, Gayatri Ganesan, M RS Rao BMC Molecular Biology 2009, 10 :64 (1 [Abstract ] [Provisional PDF ]
Research article
Selection and evaluation of reference genes for improved interrogation of microbial transcriptomes: case study with the extremophile Acidithiobacillus ferrooxidans. Pamela A Nieto, Paulo C Covarrubias, Eugenia Jedlicki, David S Holmes, Raquel Quatrini BMC Molecular Biology 2009, 10 :63 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Construction of an adult barnacle (Balanus amphitrite) cDNA library and selection of reference genes for quantitative RT-PCR studies Tristano Bacchetti De Gregoris, Marco Borra, Elio Biffali, Thomas Bekel, J GRANT Burgess, Richard R Kirby, Anthony S Clare BMC Molecular Biology 2009, 10 :62 (24 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
A strategy for enrichment of claudins based on their affinity to Clostridium perfringens enterotoxin Dorte Lohrberg, Eberhard Krause, Michael Schumann, Jorg Piontek, Lars Winkler, Ingolf E Blasig, Reiner F Haseloff BMC Molecular Biology 2009, 10 :61 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Elongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeast Igor A Valouev, Gleb V Fominov, Elizaveta E Sokolova, Vladimir N Smirnov, Michael D Ter-Avanesyan BMC Molecular Biology 2009, 10 :60 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification, characterization and expression of novel Sex Hormone Binding Globulin alternative first exons in the human prostate Tomas Pinos, Anna Barbosa-Desongles, Antoni Hurtado, Albert Santamaria-Martinez, Ines de Torres, Joan Morote, Jaume Reventos, Francina Munell BMC Molecular Biology 2009, 10 :59 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Nuclear accumulation of polyglutamine disease proteins and neuropathology Lauren S Havel, Shihua Li, Xiao-Jiang Li Molecular Brain 2009, 2 :21 (3 [Abstract ] [Provisional PDF ]
Research article
Differential expression proteomics to investigate responses and resistance to Orobanche crenata in Medicago truncatula Ma Angeles Castillejo, Ana M. Maldonado, Eliane Dumas-Gaudot, Monica Fernandez-Aparicio, Rafael Susin, Diego Rubiales, Jesus V. Jorrin BMC Genomics 2009, 10 :294 (3 [Abstract ] [Provisional PDF ]
Research
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers Chun Hei Antonio Cheung, Huang-Hui Chen, Ching-Chuan Kuo, Chi-Yen Chang, Mohane S Coumar, Hsing-Pang Hsieh, Jang-Yang Chang Molecular Cancer 2009, 8 :43 (3 [Abstract ] [Provisional PDF ]
Review
Regulation of DNA replication by the S-Phase DNA damage checkpoint Nicholas Willis, Nicholas Rhind Cell Division 2009, 4 :13 (3 [Abstract ] [Provisional PDF ]
Research article
Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunits Suryadevara Rao, Randy D Dinkins, Arthur G Hunt BMC Cell Biology 2009, 10 :51 (2 [Abstract ] [Provisional PDF ]
Research article
Selection of reference genes for quantitative real time PCR expression studies in the apomictic and sexual grass Brachiaria brizantha Erica DUARTE Silveira, Marcio Alves-Ferreira, Larissa ARRAIS Guimaraes, Felipe RODRIGUES da Silva, Vera TAVARES DE CAMPOS Carneiro BMC Plant Biology 2009, 9 :84 (2 [Abstract ] [Provisional PDF ]
Technical Note
Construction and analysis of cotton (Gossypium arboreum L.) drought-related cDNA library Ling Zhang, Fu-Guang Li, Chuan-Liang Liu, Chao-Jun Zhang, Xue-Yan Zhang BMC Research Notes 2009, 2 :120 (2 [Abstract ] [Provisional PDF ]
Research
Resveratrol exhibits a strong cytotoxic activity in cultured cells and has an antiviral action against polyomavirus: potential clinical use Valerio Berardi, Francesca Ricci, Mauro Castelli, Gaspare Galati, Gianfranco Risuleo Journal of Experimental & Clinical Cancer Research 2009, 28 :96 (1 [Abstract ] [Provisional PDF ]
Research article
Broad-range PCR, cloning and sequencing of the full 16S rRNA gene for detection of bacterial DNA in synovial fluid samples of Tunisian patients with reactive and undifferentiated arthritis Mariam Siala, Radhouane Gdoura, Hela Fourati, Markus Rihl, Benoit Jaulhac, Mohamed Younes, Jean Sibilia, Sofien Baklouti, Naceur Bargaoui, Slaheddine Sellami, Abdelghani Sghir, Adnane Hammami Arthritis Research & Therapy 2009, 11 :R102 (1 [Abstract ] [Provisional PDF ]
Short Report
Identification Of Osteopontin-Dependent Signaling Pathways In Human Breast Cancer Zhiyong Mi, Hongtao Guo, Paul C Kuo BMC Research Notes 2009, 2 :119 (1 [Abstract ] [Provisional PDF ]
Featured articles 
