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Image of the Month – July 2006
Wild-type mouse embryo 9.5 days post coitum. To assess the effect of targeted cubilin knockdown on blood vessel formation, embryos were immunolabeled with anti-PECAM-1, an endothelial cell marker. Cubilin-deficient embryos display developmental retardation and do not advance morphologically beyond the appearance of WT 8-8.5 dpc embryos.
Adapted from: Smith et al., BMC Developmental Biology 2006,
6:30 [View article]