Loss of the retinoblastoma protein permits differentiated enteroendocrine cells to remain in the cell cycle and hyperproliferate
Intestinal section from a mouse that was heterozygous for a conditional knockout mutation of the retinoblastoma gene was stained by immunofluorescence for the cell proliferation marker Ki-67 and the enteroendocrine marker serotonin. The merged image shows staining with anti-Ki67 in green, anti-serotonin in red and DAPI in blue.
Taken from: Hai-Su Yang et al., 2007, BMC Developmental Biology [View article]
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