Table 6 |
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|
Detailed overview of the supervised analysis using CGH test. |
|||||||||
|
cytoband |
region start (bp) |
region end (bp) |
p-value |
fdr |
cytoband |
region start (bp) |
region end (bp) |
p-value |
fdr |
|
|
|||||||||
|
1p36.33 |
672780 |
1359795 |
0.04 |
0.15 |
11p14.2-p14.1 |
27033269 |
27371257 |
0.05 |
0.15 |
|
1p36.32-p36.31 |
3386389 |
6294064 |
0.03 |
0.12 |
11q13.3 |
68509550 |
69323966 |
0.04 |
0.14 |
|
1p36.21-p36.13 |
12798944 |
15683816 |
0.03 |
0.12 |
11q13.3-q13.4 |
69314721 |
70472869 |
0.04 |
0.14 |
|
1p31.2 |
67178936 |
69303906 |
0.04 |
0.14 |
11q22.1-q22.2 |
98930611 |
101405228 |
0.03 |
0.12 |
|
1p31.1 |
69815162 |
76679895 |
0.01 |
0.06 |
11q22.2-q22.3 |
102010610 |
102424014 |
0.03 |
0.12 |
|
1p31.1 |
77428804 |
77820126 |
<0.01 |
0.04 |
12q21.2 |
76570565 |
78724263 |
0.04 |
0.14 |
|
1p21.2-p21.1 |
101684496 |
104502748 |
0.03 |
0.12 |
13q21.31-q21.33 |
61335626 |
69275204 |
0.04 |
0.14 |
|
1q31.1-q31.2 |
184717073 |
188976520 |
0.01 |
0.09 |
14q21.1 |
39694531 |
42171623 |
0.02 |
0.10 |
|
1q31.2-q31.3 |
189822405 |
193082884 |
0.02 |
0.10 |
14q21.2 |
42965408 |
44043547 |
0.01 |
0.09 |
|
1q31.3 |
193336091 |
194242465 |
0.01 |
0.08 |
14q21.2-q21.3 |
45258184 |
48298851 |
0.03 |
0.12 |
|
1q31.3 |
195068870 |
195629725 |
0.03 |
0.12 |
15q14 |
33841939 |
35953471 |
0.04 |
0.14 |
|
3p26.3 |
46140 |
2377366 |
<0.01 |
0.03 |
15q22.2 |
57373165 |
61214280 |
0.02 |
0.09 |
|
3p24.3 |
17181327 |
18148477 |
<0.01 |
0.03 |
15q23 |
65816865 |
68768615 |
0.02 |
0.09 |
|
3p24.3 |
19033520 |
21742232 |
<0.01 |
0.03 |
15q23-q24.2 |
69188639 |
73645336 |
0.05 |
0.15 |
|
3p24.3-p24.1 |
22747912 |
27531283 |
0.02 |
0.10 |
15q24.2-q25.2 |
74334873 |
81024206 |
0.03 |
0.12 |
|
3p21.31 |
46545403 |
47371983 |
0.05 |
0.15 |
16p13.2-p13.12 |
8777494 |
12522798 |
0.05 |
0.15 |
|
3p21.31 |
47384745 |
50114898 |
0.04 |
0.14 |
16p11.2 |
28675396 |
31163676 |
<0.01 |
0.04 |
|
3p21.31-p21.2 |
50533656 |
51418837 |
0.01 |
0.09 |
16q24.1 |
82993991 |
83622386 |
0.05 |
0.15 |
|
3p21.31-p21.2 |
51390596 |
52007218 |
0.02 |
0.09 |
16q24.1 |
84123856 |
84922042 |
0.02 |
0.09 |
|
3p21.1 |
52658450 |
53621497 |
0.01 |
0.09 |
16q24.2-q24.3 |
86986672 |
87452904 |
0.03 |
0.12 |
|
3p12.3 |
76450939 |
79097142 |
0.02 |
0.09 |
16q24.3 |
87848795 |
88465228 |
0.02 |
0.09 |
|
3p12.3-p12.2 |
79197544 |
82066233 |
<0.01 |
0.04 |
16q24.3 |
88398231 |
88613383 |
0.01 |
0.07 |
|
3p12.2-p12.1 |
82657794 |
84801874 |
<0.01 |
0.03 |
17p13.3 |
427024 |
1071560 |
<0.01 |
0.03 |
|
3p12.1-p11.2 |
85234579 |
87730259 |
<0.01 |
0.03 |
17p13.3-p13.2 |
2026966 |
4169913 |
0.04 |
0.14 |
|
3p11.1 |
88915283 |
89771786 |
<0.01 |
0.04 |
17p13.2 |
4810523 |
5166678 |
0.01 |
0.09 |
|
3q11.2 |
95569618 |
96250439 |
0.01 |
0.05 |
17p13.1 |
6780962 |
7477414 |
<0.01 |
0.03 |
|
3q25.1-q25.33 |
151508469 |
161536133 |
0.03 |
0.12 |
17p13.1 |
7436435 |
7682367 |
<0.01 |
0.03 |
|
3q25.33-q26.1 |
162044657 |
164516640 |
0.03 |
0.12 |
17p11.2 |
17343389 |
19251691 |
0.04 |
0.14 |
|
3q26.1 |
165289729 |
167697600 |
0.05 |
0.15 |
17q11.2 |
23133763 |
28423820 |
0.02 |
0.09 |
|
3q26.31-q26.32 |
174848631 |
180449332 |
0.05 |
0.15 |
17q11.2-q12 |
28664889 |
29147086 |
0.02 |
0.09 |
|
4p15.32-p14 |
17799729 |
36260048 |
0.02 |
0.11 |
17q25.1 |
69709369 |
71238958 |
0.01 |
0.09 |
|
4p14 |
36998587 |
37497326 |
0.01 |
0.09 |
17q25.1-q25.3 |
71406319 |
77588058 |
0.03 |
0.12 |
|
4p14 |
37851044 |
38103870 |
0.02 |
0.11 |
18q11.2 |
21431314 |
21774952 |
0.01 |
0.05 |
|
4p14-p12 |
38087293 |
46781512 |
0.01 |
0.09 |
18q11.2 |
22104619 |
22931012 |
<0.01 |
0.04 |
|
4q12 |
58332155 |
59148507 |
0.04 |
0.14 |
18q12.1 |
23970882 |
24526449 |
0.02 |
0.10 |
|
4q12-q13.1 |
59679465 |
62653308 |
0.02 |
0.10 |
18q12.1 |
25034674 |
26878315 |
0.01 |
0.08 |
|
4q13.3 |
74322497 |
76429795 |
0.03 |
0.12 |
18q12.1 |
27447009 |
28415095 |
0.01 |
0.09 |
|
4q13.3-q21.21 |
76495364 |
79353372 |
0.02 |
0.09 |
18q12.1 |
29409483 |
30219417 |
0.01 |
0.09 |
|
4q21.21 |
79222718 |
80683287 |
0.03 |
0.12 |
18q12.1-q12.2 |
30773824 |
31588529 |
0.01 |
0.06 |
|
4q33-q34.3 |
172094999 |
178721484 |
0.02 |
0.10 |
18q22.1 |
60340433 |
61310295 |
0.03 |
0.12 |
|
4q34.3 |
178969859 |
179599683 |
0.01 |
0.09 |
18q22.1 |
61623805 |
62645202 |
0.03 |
0.12 |
|
4q34.3 |
180819690 |
183096645 |
0.02 |
0.10 |
18q22.1-q22.3 |
63092764 |
68041625 |
0.03 |
0.12 |
|
4q35.1 |
184503994 |
186178296 |
0.03 |
0.12 |
19p13.3 |
134914 |
913289 |
0.01 |
0.08 |
|
5q11.2 |
50971745 |
52055659 |
0.04 |
0.14 |
19p13.3 |
902641 |
5009969 |
<0.01 |
0.04 |
|
5q11.2 |
52909242 |
56437163 |
0.03 |
0.12 |
19p13.3 |
5663923 |
6519297 |
<0.01 |
0.01 |
|
5q11.2-q12.1 |
56921490 |
58947885 |
0.02 |
0.09 |
19p13.3-p13.2 |
6523443 |
9826740 |
<0.01 |
<0.01 |
|
5q14.3 |
82802677 |
86118543 |
0.05 |
0.15 |
19p13.2-p13.12 |
10248852 |
15116365 |
<0.01 |
0.03 |
|
5q23.2 |
122463056 |
123527915 |
0.05 |
0.15 |
19p13.12-p13.11 |
15415833 |
17777501 |
<0.01 |
0.01 |
|
7p22.1-p21.3 |
6983150 |
7932634 |
<0.01 |
0.02 |
19p13.11 |
18202507 |
19023254 |
<0.01 |
0.03 |
|
7p21.3-p21.2 |
9256088 |
14085902 |
<0.01 |
<0.01 |
19p12 |
19877150 |
21504328 |
0.01 |
0.05 |
|
7p21.2-p21.1 |
14342152 |
19957111 |
<0.01 |
0.01 |
19p12 |
22133662 |
22949959 |
0.01 |
0.05 |
|
7q22.1 |
98651132 |
100929260 |
<0.01 |
0.03 |
19q12 |
33315121 |
33507712 |
0.02 |
0.10 |
|
8q24.21 |
130562467 |
131126185 |
0.05 |
0.15 |
19q12 |
34159370 |
34664148 |
0.02 |
0.11 |
|
8q24.22 |
131641447 |
133561490 |
0.01 |
0.09 |
19q12 |
34960906 |
35766560 |
0.02 |
0.11 |
|
8q24.22 |
134537164 |
136154996 |
0.02 |
0.11 |
19q12-q13.11 |
36958851 |
37518517 |
0.05 |
0.15 |
|
8q24.22-q24.23 |
136472354 |
138543270 |
0.04 |
0.14 |
19q13.12-q13.13 |
40883472 |
43004503 |
0.03 |
0.13 |
|
8q24.3 |
141395868 |
142790557 |
0.01 |
0.05 |
19q13.2-q13.32 |
46498596 |
50725496 |
0.03 |
0.12 |
|
8q24.3 |
144790054 |
145357620 |
0.01 |
0.09 |
19q13.32-q13.33 |
52665374 |
54718281 |
0.03 |
0.12 |
|
8q24.3 |
145585590 |
145953950 |
0.02 |
0.11 |
19q13.33-q13.43 |
55461670 |
63771717 |
<0.01 |
0.01 |
|
8q24.3 |
145893230 |
146238749 |
0.04 |
0.14 |
21q11.2-q21.1 |
13857799 |
18774434 |
<0.01 |
0.03 |
|
9p24.1-p23 |
8398601 |
9689968 |
0.04 |
0.14 |
21q21.1 |
20982315 |
21411332 |
<0.01 |
0.03 |
|
9p23 |
9684353 |
10554235 |
0.04 |
0.14 |
21q21.1-q21.2 |
22151920 |
22943367 |
<0.01 |
0.03 |
|
10q22.1 |
70824040 |
71674097 |
0.03 |
0.12 |
21q21.2 |
23491399 |
25568510 |
<0.01 |
0.01 |
|
10q22.1 |
72033907 |
73573433 |
0.02 |
0.09 |
21q21.3 |
26174732 |
26923374 |
0.02 |
0.09 |
|
10q26.3 |
135110821 |
135301208 |
0.03 |
0.12 |
21q21.3-q22.11 |
28596969 |
30855176 |
0.03 |
0.12 |
|
11p15.5 |
178227 |
626401 |
0.01 |
0.05 |
22q13.33 |
48473404 |
49397088 |
0.04 |
0.15 |
|
11p15.5 |
1299306 |
1785278 |
<0.01 |
0.03 |
|||||
|
|
|||||||||
|
In total, 133 regions were significantly different (p < 0.05 and fdr≤0.15) between UK and native SA tumors. The chromosomal regions, including the start and end positions, and the fdr rates are listed. |
|||||||||
|
Buffart et al. BMC Medical Genomics 2011 4:7 doi:10.1186/1755-8794-4-7 |
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