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24 result(s) for 'author#Cornelis JH van de Velde' within BMC
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Citation: Critical Care 2008 12(Suppl 2):P343
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Citation: Critical Care 2008 12(Suppl 2):P506 -
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Citation: Critical Care 2008 12(Suppl 2):P370 -
34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): part 1
Citation: Journal for ImmunoTherapy of Cancer 2019 7(Suppl 1):282 -
42nd International Symposium on Intensive Care & Emergency Medicine
Citation: Critical Care 2023 27(Suppl 1):119 -
Discussion on the use of taxanes for treatment of breast cancers in BRCA1 mutations carriers
Citation: Hereditary Cancer in Clinical Practice 2007 5:119 -
The influence of micrometastases on prognosis and survival in stage I-II colon cancer patients: the Enroute⊕ Study
The presence of lymph node metastases remains the most reliable prognostic predictor and the gold indicator for adjuvant treatment in colon cancer (CC). In spite of a potentially curative resection, 20 to 30% ...
Citation: BMC Surgery 2011 11:11 -
Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect - a histopathological and immunohistochemical study
Invasion and metastasis is a complex process governed by the interaction of genetically altered tumor cells and the immunological and inflammatory host reponse. Specific T-cells directed against tumor cells an...
Citation: BMC Cancer 2001 1:7 -
Efficacy of adjuvant chemotherapy according to hormone receptor status in young patients with breast cancer: a pooled analysis
Breast cancer at a young age is associated with an unfavorable prognosis. Very young patients with breast cancer therefore are advised to undergo adjuvant chemotherapy irrespective of tumor stage or grade. How...
Citation: Breast Cancer Research 2007 9:R70 -
Neo-adjuvant chemotherapy followed by surgery and chemotherapy or by surgery and chemoradiotherapy for patients with resectable gastric cancer (CRITICS)
Radical surgery is the cornerstone in the treatment of resectable gastric cancer. The Intergroup 0116 and MAGIC trials have shown benefit of postoperative chemoradiation and perioperative chemotherapy, respect...
Citation: BMC Cancer 2011 11:329 -
Impact of established prognostic factors and molecular subtype in very young breast cancer patients: pooled analysis of four EORTC randomized controlled trials
Young age at the time of diagnosis of breast cancer is an independent factor of poor prognosis. In many treatment guidelines, the recommendation is to treat young patients with adjuvant chemotherapy regardless...
Citation: Breast Cancer Research 2011 13:R68 -
Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles
The molecular determinants of carcinogenesis, tumor progression and patient prognosis can be deduced from simultaneous comparison of thousands of genes by microarray analysis. However, the presence of stroma c...
Citation: BMC Genomics 2005 6:142 -
High-resolution analysis of HLA class I alterations in colorectal cancer
Previous studies indicate that alterations in Human Leukocyte Antigen (HLA) class I expression are frequent in colorectal tumors. This would suggest serious limitations for immunotherapy-based strategies invol...
Citation: BMC Cancer 2006 6:233 -
Gastric cancers of Western European and African patients show different patterns of genomic instability
Infection with H. pylori is important in the etiology of gastric cancer. Gastric cancer is infrequent in Africa, despite high frequencies of H. pylori infection, referred to as the African enigma. Variation in en...
Citation: BMC Medical Genomics 2011 4:7 -
Histone trimethylation at H3K4, H3K9 and H4K20 correlates with patient survival and tumor recurrence in early-stage colon cancer
Post-translational modification of histone tails by methylation plays an important role in tumorigenesis. In this study, we investigated the nuclear expression of H3K4me3, H3K9me3 and H4K20me3 in early-stage c...
Citation: BMC Cancer 2014 14:531 -
Introduction of a breast cancer care programme including ultra short hospital stay in 4 early adopter centres: framework for an implementation study
Whereas ultra-short stay (day care or 24 hour hospitalisation) following breast cancer surgery was introduced in the US and Canada in the 1990s, it is not yet common practice in Europe. This paper describes th...
Citation: BMC Cancer 2007 7:117 -
DNA copy number profiles of gastric cancer precursor lesions
Chromosomal instability (CIN) is the most prevalent type of genomic instability in gastric tumours, but its role in malignant transformation of the gastric mucosa is still obscure. In the present study, we set...
Citation: BMC Genomics 2007 8:345 -
NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study
Cell surface NKG2D ligands (NKG2DL) bind to the activating NKG2D receptor present on NK cells and subsets of T cells, thus playing a role in initiating an immune response. We examined tumor expression and prog...
Citation: BMC Cancer 2012 12:24 -
Expression of uPAR in tumor-associated stromal cells is associated with colorectal cancer patient prognosis: a TMA study
The receptor for urokinase-type plasminogen activator (uPAR) is associated with cancer development and progression. Within the tumor microenvironment uPAR is expressed by malignant cells as well as tumor-assoc...
Citation: BMC Cancer 2014 14:269 -
High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients
Breast cancer is a heterogeneous disease with a highly variable clinical outcome in which both genetic and epigenetic changes have critical roles. We investigated tumor expression levels of histone-modifying e...
Citation: BMC Cancer 2014 14:604