Figure 5.

Computation of subnetwork alignment score. The alignment score between subnetwork Sp and Sq is the summation of the similarity score between all pairs of matched shortest paths ((i1, i2) and (j1, j2) in the figure), calculated based on the sequence similarities (E(i1, j1) and E(i2, j2)) and the distances in the subnetworks (dist(i1, i2) and dist(j1, j2)).

Cai et al. BMC Systems Biology 2012 6(Suppl 3):S5   doi:10.1186/1752-0509-6-S3-S5