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This article is part of the supplement: The International Conference on Intelligent Biology and Medicine (ICIBM): Systems Biology

Open Access Research

A cross-species analysis method to analyze animal models' similarity to human's disease state

Shuhao Yu1, Lulu Zheng45, Yun Li2, Chunyan Li3, Chenchen Ma2, Yixue Li125, Xuan Li2* and Pei Hao35*

Author Affiliations

1 College of Life Science and Biotechnology, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai 200240, P.R.China

2 Key Lab of Systems Biology/Key Laboratory of Synthetic Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, P.R.China

3 Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, P.R.China

4 College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, P.R.China

5 Shanghai Center for Bioinformation Technology, Shanghai, P.R.China

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BMC Systems Biology 2012, 6(Suppl 3):S18  doi:10.1186/1752-0509-6-S3-S18

Published: 17 December 2012

Additional files

Additional file 1:

All GOMs of alpha-estradiol, monoden and fulvestrant in our result of Alzheimer case. The yellow GO modules are associated with lipid or sterol process, indicating these modules involved Alzheimer disease may act through these process. The green GO modules are only enriched in the result of fulvestrant.

Format: XLS Size: 25KB Download file

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