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This article is part of the supplement: Selected articles from the Third International Symposium on Optimization and Systems Biology

Open Access Proceedings

Computational inference and analysis of genetic regulatory networks via a supervised combinatorial-optimization pattern

Binhua Tang1, Xuechen Wu2, Ge Tan3, Su-Shing Chen4, Qing Jing5 and Bairong Shen6*

Author Affiliations

1 Department of Bioinformatics, Tongji University, Shanghai, 212003, China

2 Institute of Protein Research, Tongji University, Shanghai, 212003, China

3 Department of Computer Science, ETH, Zurich, 8092, Switzerland

4 CISE and Systems Biology Lab, University of Florida, Gainesville, FLA, 32611, USA

5 Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China

6 Center for Systems Biology, Soochow University, Suzhou, 215006, China

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BMC Systems Biology 2010, 4(Suppl 2):S3  doi:10.1186/1752-0509-4-S2-S3

Published: 13 September 2010

Additional files

Additional file 1:

The calculated mutual information matrix for 276 gene pairs from the 24 cell-cycle genes.

Format: DOC Size: 78KB Download file

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Additional file 2:

The descending-order sorted mutual information, correlation coefficient and corresponding P-value statistics.

Format: DOC Size: 109KB Download file

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Additional file 3:

The three-dimensional distribution for authentic (APGs), questionable (QPGs), and unauthentic pairwise genes (UPGs).

Format: DOC Size: 54KB Download file

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Additional file 4:

The phase-shift statistics for the group APGs.

Format: DOC Size: 46KB Download file

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Additional file 5:

Associativity measure statistics for the group APGs from the Saccharomyces cerevisiae cell cycle microarray dataset.

Format: DOC Size: 121KB Download file

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Additional file 6:

Mutual information matrix for the triplicate MOTL4 microarray experiments.

Format: DOC Size: 64KB Download file

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Additional file 7:

The descending-sorted mutual information, correlation coefficient and corresponding P-value statistics.

Format: DOC Size: 90KB Download file

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Open Data

Additional file 8:

The three-dimensional distribution for authentic (APGs), questionable (QPGs), and unauthentic pairwise genes (UPGs).

Format: DOC Size: 225KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 9:

The phase-shift statistics for the group APGs.

Format: DOC Size: 59KB Download file

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Open Data

Additional file 10:

The constructed genetic map with gain threshold at 1.

Format: DOC Size: 196KB Download file

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Additional file 11:

Associativity measure statistics for the group APGs in the human cancer MOTL4 cell cycle microarray dataset.

Format: DOC Size: 139KB Download file

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Open Data