Table 6 |
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|
Weight management, blood glucose and blood lipids: Saccharide vs Saccharide |
||||
|
Comparison |
Population |
Timepoint (week) |
No of participants |
MD (95% CI) |
|
|
||||
|
BMI, kg/m2 |
||||
|
Honey vs Sucrose |
Overweight/Obese |
4 |
55 |
-0.5 (-3.1,2.1) |
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
-0.04 (-0.4,0.3) |
|
Weight, kg |
||||
|
Fructose vs Glucose |
General |
6 |
24 |
0.1 (-3.4,3.6) |
|
Fructose vs Glucose |
General |
1 |
11 |
-0.4 (-3.1,2.3) |
|
FOS vs Glucose |
DM2 |
3 |
20 |
0.2 (-5.2,5.6) |
|
FOS vs Sucrose |
General |
4 |
12 |
1.0 (-2.4,4.4) |
|
Honey vs Sucrose |
Overweight/Obese |
4 |
55 |
-1.5 (-6.9,3.9) |
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
-0.06 (-0.9,0.8) |
|
Sucrose vs Glucose |
General |
2 |
10 |
0.2 (-0.07,0.4) |
|
Energy Intake, kcal |
||||
|
FOS vs Glucose |
DM2 |
3 |
20 |
-139 (-399,122) |
|
FOS vs Sucrose |
General |
4 |
12 |
-56 (-156,43) |
|
HbA1C, % |
||||
|
FOS vs Sucrose |
DM2 |
4 |
10 |
0.17 (-0.59,0.93) |
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
0.01 (-0.05,0.07) |
|
HOMA Index |
||||
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
-0.44 (-0.76,-0.12) |
|
Total Cholesterol, mmol/L |
||||
|
Fructose vs Glucose |
General |
1 |
11 |
0.10 (-0.24,0.44) |
|
FOS vs Glucose |
DM2 |
3 |
20 |
0.20 (-0.27,0.67) |
|
FOS vs Sucrose |
DM2 |
4 |
10 |
0.15 (-0.24,0.54) |
|
FOS vs Sucrose |
General |
4 |
12 |
0.31 (0.03,0.59) |
|
Honey vs Sucrose |
Overweight/Obese |
4 |
55 |
-0.11 (-0.26,0.05) |
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
-0.10 (-0.17,-0.02) |
|
Tagatose vs Sucrose |
General |
4 |
12 |
-0.11 (-0.51,0.29) |
|
LDL Cholesterol, mmol/L |
||||
|
Fructose vs Glucose |
General |
1 |
11 |
0 (-0.17,0.17) |
|
FOS vs Sucrose |
DM2 |
4 |
10 |
0.13 (-0.21,0.47) |
|
Honey vs Sucrose |
Overweight/Obese |
4 |
55 |
-0.03 (-0.22,0.16) |
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
-0.02 (-0.08,0.04) |
|
Tagatose vs Sucrose |
General |
4 |
12 |
0.09 (-0.26,0.44) |
|
HDL Cholesterol, mmol/L |
||||
|
Fructose vs Glucose |
General |
1 |
11 |
0 (-0.17,0.17) |
|
FOS vs Sucrose |
General |
4 |
12 |
-0.06 (-0.14,0.02) |
|
FOS vs Sucrose |
DM2 |
4 |
10 |
0.07 (-0.03,0.17) |
|
Honey vs Sucrose |
Overweight/Obese |
4 |
55 |
0.01 (-0.12,0.14) |
|
Isomaltulose/Sucrose vs Sucrose |
General |
12 |
50 |
-0.02 (-0.05,0.01) |
|
Tagatose vs Sucrose |
General |
4 |
12 |
-0.17 (-0.28,0.06) |
|
Triglycerides, mmol/L |
||||
|
FOS vs Glucose |
DM2 |
3 |
20 |
0.12 (-0.30,0.54) |
|
FOS vs Sucrose |
General |
4 |
12 |
0.18 (-0.03,0.39) |
|
FOS vs Sucrose |
DM2 |
4 |
10 |
-0.18 (-0.38,0.02) |
|
Honey vs Sucrose |
Overweight/Obese |
4 |
55 |
-0.10 (-0.22,0.02) |
|
Isomaltulose vs Sucrose |
General |
12 |
50 |
-0.27 (-0.44,-0.10) |
|
|
||||
|
*Aspartame, acesulfame, cyclamate, saccharin DM1 Type 1 Diabetes Mellitus, DM2 Type 2 Diabetes Mellitus, BMI Body mass index, HbA1C Glycated hemoglobin, HOMA Homeostatic Model Assessment, MD Mean difference, CI Confidence interval Statistically significant results are bolded. |
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|
Wiebe et al. BMC Medicine 2011 9:123 doi:10.1186/1741-7015-9-123 |
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