Table 6

Weight management, blood glucose and blood lipids: Saccharide vs Saccharide

Comparison

Population

Timepoint (week)

No of participants

MD (95% CI)


BMI, kg/m2

Honey vs Sucrose

Overweight/Obese

4

55

-0.5 (-3.1,2.1)

Isomaltulose/Sucrose vs Sucrose

General

12

50

-0.04 (-0.4,0.3)

Weight, kg

Fructose vs Glucose

General

6

24

0.1 (-3.4,3.6)

Fructose vs Glucose

General

1

11

-0.4 (-3.1,2.3)

FOS vs Glucose

DM2

3

20

0.2 (-5.2,5.6)

FOS vs Sucrose

General

4

12

1.0 (-2.4,4.4)

Honey vs Sucrose

Overweight/Obese

4

55

-1.5 (-6.9,3.9)

Isomaltulose/Sucrose vs Sucrose

General

12

50

-0.06 (-0.9,0.8)

Sucrose vs Glucose

General

2

10

0.2 (-0.07,0.4)

Energy Intake, kcal

FOS vs Glucose

DM2

3

20

-139 (-399,122)

FOS vs Sucrose

General

4

12

-56 (-156,43)

HbA1C, %

FOS vs Sucrose

DM2

4

10

0.17 (-0.59,0.93)

Isomaltulose/Sucrose vs Sucrose

General

12

50

0.01 (-0.05,0.07)

HOMA Index

Isomaltulose/Sucrose vs Sucrose

General

12

50

-0.44 (-0.76,-0.12)

Total Cholesterol, mmol/L

Fructose vs Glucose

General

1

11

0.10 (-0.24,0.44)

FOS vs Glucose

DM2

3

20

0.20 (-0.27,0.67)

FOS vs Sucrose

DM2

4

10

0.15 (-0.24,0.54)

FOS vs Sucrose

General

4

12

0.31 (0.03,0.59)

Honey vs Sucrose

Overweight/Obese

4

55

-0.11 (-0.26,0.05)

Isomaltulose/Sucrose vs Sucrose

General

12

50

-0.10 (-0.17,-0.02)

Tagatose vs Sucrose

General

4

12

-0.11 (-0.51,0.29)

LDL Cholesterol, mmol/L

Fructose vs Glucose

General

1

11

0 (-0.17,0.17)

FOS vs Sucrose

DM2

4

10

0.13 (-0.21,0.47)

Honey vs Sucrose

Overweight/Obese

4

55

-0.03 (-0.22,0.16)

Isomaltulose/Sucrose vs Sucrose

General

12

50

-0.02 (-0.08,0.04)

Tagatose vs Sucrose

General

4

12

0.09 (-0.26,0.44)

HDL Cholesterol, mmol/L

Fructose vs Glucose

General

1

11

0 (-0.17,0.17)

FOS vs Sucrose

General

4

12

-0.06 (-0.14,0.02)

FOS vs Sucrose

DM2

4

10

0.07 (-0.03,0.17)

Honey vs Sucrose

Overweight/Obese

4

55

0.01 (-0.12,0.14)

Isomaltulose/Sucrose vs Sucrose

General

12

50

-0.02 (-0.05,0.01)

Tagatose vs Sucrose

General

4

12

-0.17 (-0.28,0.06)

Triglycerides, mmol/L

FOS vs Glucose

DM2

3

20

0.12 (-0.30,0.54)

FOS vs Sucrose

General

4

12

0.18 (-0.03,0.39)

FOS vs Sucrose

DM2

4

10

-0.18 (-0.38,0.02)

Honey vs Sucrose

Overweight/Obese

4

55

-0.10 (-0.22,0.02)

Isomaltulose vs Sucrose

General

12

50

-0.27 (-0.44,-0.10)


*Aspartame, acesulfame, cyclamate, saccharin

DM1 Type 1 Diabetes Mellitus, DM2 Type 2 Diabetes Mellitus, BMI Body mass index, HbA1C Glycated hemoglobin, HOMA Homeostatic Model Assessment, MD Mean difference, CI Confidence interval

Statistically significant results are bolded.

Wiebe et al. BMC Medicine 2011 9:123   doi:10.1186/1741-7015-9-123

Open Data