To accompany their BMC conference series on Metabolism, diet and disease, this year with the special theme of cancer and metabolism, the two conference host journals, BMC Biology and BMC Medicine, have launched a thematic series of publications aimed at showing how basic research on the biochemistry, cell biology and genetics of metabolism can address the major health problems of cancer, obesity, cardiovascular disease, diabetes and insulin resistance, and how the therapeutic and nutritional implications can inform the clinical management and treatment of these diseases. The series includes original research, review, comment and opinion pieces, as well as interviews and Q&As, and we welcome further research submissions on these topics. (Video) The obesity-cancer connection. Panel discussion from 'Metabolism Diet and Disease' held in Washington DC, May 29-31 2012. The opinions presented by the panel are those of the individuals and do not represent an endorsement of any organization or product.