Table 5 |
||||
|
Weight management, blood glucose and blood lipids: Non-caloric versus Sucrose |
||||
|
Non-caloric sweetener |
Population |
Timepoint (week) |
No of participants |
MD (95% CI) |
|
|
||||
|
BMI, kg/m2 |
||||
|
Aspartame |
General |
4 |
133 |
-0.3 (-1.1,0.5) |
|
Mixturea |
Overweight |
10 |
41 |
-0.9 (-1.5,-0.4) |
|
Weight, kg |
||||
|
Cyclamate |
DM1 |
4 |
10 |
0.8 (-3.3,4.9) |
|
Mixture |
Overweight |
10 |
41 |
-2.6 (-3.7,-1.5) |
|
Day Energy Intake, kcal |
||||
|
Aspartame |
General |
4 |
133 |
-283 (-414,-153) |
|
Mixture |
Overweight |
10 |
41 |
-491 (-806,-177) |
|
HbA1C, % |
||||
|
Cyclamate |
DM1 |
4 |
10 |
-0.02 (-0.4,0.3) |
|
HOMA Index |
||||
|
Mixture |
Overweight |
10 |
41 |
-0.20 (-0.58,0.18) |
|
Total Cholesterol, mmol/L |
||||
|
Cyclamate |
DM1 |
4 |
10 |
-0.34 (-0.87,0.19) |
|
HDL Cholesterol, mmol/L |
||||
|
Cyclamate |
DM1 |
4 |
10 |
-0.05 (-0.32,0.22) |
|
Triglycerides, mmol/L |
||||
|
Cyclamate |
DM1 |
4 |
10 |
-0.02 (-0.16,0.12) |
|
Mixture |
Overweight |
10 |
41 |
-0.26 (-0.85,0.34) |
|
|
||||
|
aAspartame, acesulfame, cyclamate, saccharin DM1, Type 1 Diabetes Mellitus; DM2, Type 2 Diabetes Mellitus; BMI, Body mass index; HbA1C, Glycated haemoglobin; HOMA, Homeostatic Model Assessment; MD, Mean difference; CI, Confidence interval Statistically significant results are bolded. |
||||
|
Wiebe et al. BMC Medicine 2011 9:123 doi:10.1186/1741-7015-9-123 |
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