Table 1

Serum biological indicators and bone-mineral density between rats on the normal-calcium diet and rats on thelow-calcium diet.

Normal-calcium group

Low-calcium group



Week 4

Week 8

Week12

Week 4

Week 8

Week 12


Calcium, mmol/l

2.53 ± 0.26

2.55 ± 0.19

2.56 ± 0.28

2.55 ± 0.23

2.51 ± 0.17

2.31 ± 0.28*

Phosphorus, mg/l

9.38 ± 1.94

9.29 ± 2.35

9.17 ± 2.11

9.29 ± 2.03

8.85 ± 1.60

8.67 ± 2.03

AP, U/l

85.8 ± 21.0

82.4 ± 14.2

80.1 ± 16.3

96.6 ± 17.9

111.7 ± 20.3*

117.8 ± 17.9*

PTH, pg/ml

45.6 ± 6.08

42.3 ± 2.22

31.2 ± 1.75

59.4 ± 6.87*

53.7 ± 1.95*

42.8 ± 2.13*

1,25, OH2D3, pg/ml

70.7 ± 14.9

71.6 ± 18.1

72.2 ± 19.9

87.2 ± 23.1*

120.2 ± 26.4*

121.3 ± 19.1*

FGF23, pg/ml

-

-

211 ± 9.28

-

-

234 ± 14.44*

BMD, g/cm2

0.258 ± 0.02

0.285 ± 0.02

0.298 ± 0.02

0.254 ± 0.03

0.277 ± 0.01

0.262 ± 0.03*


Abbreviations: AP, alkaline phosphatase; BMD, bone-mineral density; FGF23, fibroblast growth factor 23; LCG, low-calcium group; NCG, normal-calcium group, PTH, parathyroid hormone. *Significant differences (P<0.05) for mean values of LCG compared with NCG at the same time points.

Wang et al. BMC Medicine 2013 11:86   doi:10.1186/1741-7015-11-86

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