Table 1

Demographic, clinical and neuropsychological characteristics in multiple sclerosis patients with positive and negative diagnosis of chronic cerebrospinal venous insufficiency (CCSVI)
All patients CCSVI positive CCSVI negative
number = 64 number = 45
Median Mean SD Range Mean z Mean SD Mean SD
Age 48 47.3 9.8 25 - 66 --- 46.8 9.0 47.6 10.4
Education 16 16.0 2.3 12 - 20 --- 15.8 2.3 16.1 2.3
Male/female 38/72 --- 27/38 11/34
Disease duration in years 9 10.5 8.2 01 - 41 --- 10.6 8.5 10.5 8.1
Disease course: RR/SP/PP 79/23/07 --- 48/13/03 31/10/04
EDSS 2.5 3.3 1.9 0 - 7.5 --- 3.2 1.9 3.5 2.0
Beck Depression Inventory Fast Screen 1 2.4 2.6 0 - 16 --- 2.5 2.8 2.4 2.4
Symbol Digit Modalities Test 53 53.5 11.7 9 - 74 −0.62 54.9 12.0 51.5 11.3
Paced Auditory Serial Addition Test 48 44.3 13.8 0 - 60 −0.41 45.5 12.6 42.7 15.6
CVLT2Total Learning 55 54.0 11.1 23 - 87 0.37 55.3 12.4 52.1 8.6
CVLT2Delayed Recall 12 11.5 3.2 2 - 16 0.17 11.7 3.5 11.1 2.7
BVMTR Total Learning 23 22.1 6.7 4 - 34 −0.32 22.9 6.8 20.9 6.6
BVMTR Delayed Recall 9 8.6 2.4 1 - 12 −0.63 9.0 2.3 7.9 2.5
Controlled Oral Word Association Test 37 39.1 10.9 14 - 64 0.26 39.6 11.1 38.0 10.7
Judgment of Line Orientation Test 26 24.9 3.9 12 - 30 −0.59 25.6 3.4 24.0 4.6
DKEFS Sorting Correct Sorts 11 10.7 2.2 3 - 15 −0.07 10.7 2.3 10.7 2.0
DKEFS Sorting Description Score 40 40.3 8.7 10 - 58 -0.04 40.4 9.2 40.1 7.9

BVMTR, Brief Visuospatial Memory Test, Revised, CVLT2, California Verbal Learning Test, 2nd edition, DKEFS, Delis-Kaplan Executive Function System, EDSS, Expanded disability status scale, PP, Primary progressive, RR, Relapsing-remitting, SP, Secondary progressive, SD standard deviation.

Benedict et al.

Benedict et al. BMC Medicine 2013 11:167   doi:10.1186/1741-7015-11-167

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