Correlation between GLK expression and disease activity parameters as well as cytokines in patients with adult-onset Still's disease. The correlation between the frequencies of circulating GLK-expressing T-cells and (A) disease activity score, activity parameters including (B) serum ferritin levels, (C) C-reactive protein levels and (D) soluble interleukin-2 receptor levels, and serum levels of cytokines including (E) IL-1β, (F) IL-6, (G)TNF-α and (H) IL-17A from 24 patients with adult-onset Still's disease. Correlation coefficients (γ) and P-value were obtained by the nonparametric Spearman's rank correlation test. AOSD: adult-onset Still's disease; CRP: C-reactive protein; GLK: germinal center kinase-like kinase; IL: interleukin; sIL-2R: soluble interleukin-2 receptor levels; TNF-α: tumor necrosis factor-alpha.
Chen et al. BMC Medicine 2012 10:84 doi:10.1186/1741-7015-10-84