Figure 2.

Synthesis and release of AVP and copeptin in hypothalamus and pituitary. Pro-AVP is processed in the hypothalamus, followed by two distinct release-mechanisms for the anterior and posterior pituitary. During stress, a drop in blood pressure, or a change in osmotic pressure, AVP is released into the circulation. ACTH: adrenocorticotropic hormone; AVP: arginine vasopressin.

Nickel et al. BMC Medicine 2012 10:7   doi:10.1186/1741-7015-10-7
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