Open Access Research article

Systematic review and meta-analysis of the value of initial biomarkers in predicting adverse outcome in febrile neutropenic episodes in children and young people with cancer

Robert S Phillips1*, Ros Wade1, Thomas Lehrnbecher2, Lesley A Stewart1 and Alex J Sutton3

Author Affiliations

1 Center for Reviews and Dissemination, University of York, York, UK

2 Department of Paediatric Haematology and Oncology, University of Frankfurt, Frankfurt, Germany

3 Department of Health Sciences, University of Leicester, Leicester, UK

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BMC Medicine 2012, 10:6  doi:10.1186/1741-7015-10-6

Published: 18 January 2012

Additional files

Additional file 1:

Search Strategy (Medline). The full search strategy used for the Medline database.

Format: DOCX Size: 22KB Download file

Open Data

Additional file 2:

QUADAS assessments. Full list of assessed QUADAS (diagnostic test accuracy critical appraisal) criteria for the 25 included studies.

Format: DOCX Size: 15KB Download file

Open Data

Additional file 3:

Per-study results used in meta-analysis. Individual study results used in pooled analyses presented by marker, outcome and cut-off.

Format: DOCX Size: 18KB Download file

Open Data