Schematic outline of tissue-specific biomarker identification. Protein identification in six publicly available gene and protein databases, grouped by the type of data each database is based on, followed by filtering criteria and integration of proteomic datasets to identify and prioritize candidates is outlined. ESTs: expressed sequence tags; HPA: Human Protein Atlas; IHC: immunohistochemistry; TiGER: Tissue-specific and Gene Expression and Regulation.
Prassas et al. BMC Medicine 2012 10:39 doi:10.1186/1741-7015-10-39