Table 4 

Evolution of weight and gray matter (GM) brain volume during the TransEuropeFootRace 2009 (TEFR09) 

Parameter 
Weight in kg, 7s group 
GM volume in ml, 7s group 
Weight in kg, 10s group 
GM volume in ml, 10s group 


Timepoint 1, start 
75.1 (6.8) 
670.0 (38.1) 
73.6 (6.6) 
671.7 (46.1) 
Timepoint 2, 2,400 km 
71.2 (6.3)* 
642.9 (38.8)** 
70.0 (5.8)*** 
645.5 (38.6)**** 
Timepoint 3, 4,005 km 
70.5 (6.4)* 
630.5 (42.6)** 
69.2 (5.9)*** 
630.7 (49.4)**** 
Timepoint 4, followup 
76.5 (6.2)* 
671.1 (19.5)** 
NA 
NA 
Difference, timepoint 12 
3.9 (P = 0.0002) 
27.1 (P = 0.006) 
3.6 (P = 0.0002) 
26.2 (P = 0.0013) 
Difference, timepoint 13 
4.6 (P = 0.0002) 
39.5 (P = 0.008) 
4.4 (P = 0.0002) 
40.6 (P = 0.0002) 
Difference, timepoint 23 
0.7 (0.419) 
12.4 (P = 0.172) 
0.8 (P = 0.159) 
14.4 (P = 0.042) 
Difference, timepoint 43 
6.0 (P = 0.0002) 
40.6 (P = 0.001) 
NA 
NA 
Difference, timepoint 41 
1.4 (P = 0.092) 
1.1 (P = 0.898) 
NA 
NA 


Values are mean (SD). *P <0.0001 analysis of variance for effect of time with F(3,18) = 28.42; **P <0.001 analysis of variance for effect of time with F(3,18) = 10.70; ***P <0.0001 analysis of variance for effect of time with F(2,18) = 34.19; ****P <0.0001 analysis of variance for effect of time with F(2,18) = 18.76. 10s group = tensubject group; 7s group = sevensubject group; NA = not applicable. 

Freund et al. BMC Medicine 2012 10:170 doi:10.1186/1741701510170 