Table 4

Evolution of weight and gray matter (GM) brain volume during the TransEurope-FootRace 2009 (TEFR09)

Parameter

Weight in kg, 7s group

GM volume in ml, 7s group

Weight in kg, 10s group

GM volume in ml, 10s group


Timepoint 1, start

75.1 (6.8)

670.0 (38.1)

73.6 (6.6)

671.7 (46.1)

Timepoint 2, 2,400 km

71.2 (6.3)*

642.9 (38.8)**

70.0 (5.8)***

645.5 (38.6)****

Timepoint 3, 4,005 km

70.5 (6.4)*

630.5 (42.6)**

69.2 (5.9)***

630.7 (49.4)****

Timepoint 4, follow-up

76.5 (6.2)*

671.1 (19.5)**

NA

NA

Difference, timepoint 1-2

3.9 (P = 0.0002)

27.1 (P = 0.006)

3.6 (P = 0.0002)

26.2 (P = 0.0013)

Difference, timepoint 1-3

4.6 (P = 0.0002)

39.5 (P = 0.008)

4.4 (P = 0.0002)

40.6 (P = 0.0002)

Difference, timepoint 2-3

0.7 (0.419)

12.4 (P = 0.172)

0.8 (P = 0.159)

14.4 (P = 0.042)

Difference, timepoint 4-3

6.0 (P = 0.0002)

40.6 (P = 0.001)

NA

NA

Difference, timepoint 4-1

1.4 (P = 0.092)

1.1 (P = 0.898)

NA

NA


Values are mean (SD).

*P <0.0001 analysis of variance for effect of time with F(3,18) = 28.42; **P <0.001 analysis of variance for effect of time with F(3,18) = 10.70; ***P <0.0001 analysis of variance for effect of time with F(2,18) = 34.19; ****P <0.0001 analysis of variance for effect of time with F(2,18) = 18.76.

10s group = ten-subject group; 7s group = seven-subject group; NA = not applicable.

Freund et al. BMC Medicine 2012 10:170   doi:10.1186/1741-7015-10-170

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