Table 2

Altered genes in microarray analysis in OB/OW PP adipose tissue (overall and by prostatic disease)

Probe set

Gene Name

Gene Description

Fold Change

P


All subjects

8098146

NPY5R

neuropeptide Y receptor Y5

1.80

1.49E-05

7948612

FADS1

fatty acid desaturase 1

-1.73

1.16E-04

8103494

NPY1R

neuropeptide Y receptor Y1

1.97

1.56E-04

7969050

CYSLTR2

cysteinyl leukotriene receptor 2

1.89

2.19E-04

8073633

PNPLA3

patatin-like phospholipase domain containing 3

-1.56

5.74E-04

7930181

AS3MT

arsenic (+3 oxidation state) methyltransferase

1.53

6.54E-04


BPH

8020343

ANKRD20A5

ankyrin repeat domain 20 family; member A5

-1.51

3.95E-05

8152297

ANGPT1

angiopoietin 1

1.63

2.08E-04

7937508

CD151

CD151 molecule (Raph blood group)

1.69

2.43E-04

7959102

HSPB8

heat shock 22kDa protein 8

1.51

3.88E-04

8047780

SNORA41

small nucleolar RNA; H/ACA box 41

-1.77

4.94E-04

8098146

NPY5R

neuropeptide Y receptor Y5

2.06

7.86E-04

8135909

LEP

leptin

1.95

8.00E-04


OCPCa

7997239

PDXDC2

pyridoxal-dependent decarboxylase domain containing 2

1.99

8.30E-06

7994026

NPIPL3

nuclear pore complex interacting protein-like 3

1.64

1.52E-04

8019280

PCYT2

phosphate cytidylyltransferase 2; ethanolamine

-1.54

7.55E-04


EPCa

7902400

SNORD45B

small nucleolar RNA; C/D box 45B

-4.71

2.29E-04

7980861

CATSPERB

cation channel; sperm-associated; beta

1.73

5.81E-04

8057004

PDE11A

phosphodiesterase 11A

2.59

6.68E-04

8004325

EIF5A

eukaryotic translation initiation factor 5A

-1.50

7.72E-04

7969050

CYSLTR2

cysteinyl leukotriene receptor 2

2.50

9.01E-04


Fold change and the corresponding P-value for each significant gene are presented, using the lean group as reference. The bold ones with adjusted P <0.2.

Ribeiro et al. BMC Medicine 2012 10:108   doi:10.1186/1741-7015-10-108

Open Data