Schematic summary diagram of PP adipose tissue changes in obese/overweight. Genes with altered expression are associated with the regulation of functional biological processes. Altered function likely results in chronic mild immunoinflammatory response and fat mass expansion, which ultimately impacts on prostate cancer progression. Down-regulated genes are depicted in green while up-regulated genes are shown in red. ASCs, adipose-derived stem cells; E-M-T, epithelial-to-mesenchymal transition.
Ribeiro et al. BMC Medicine 2012 10:108 doi:10.1186/1741-7015-10-108