Table 1

Patient characteristics

Parameter


Patients, n

120

Male, n (%)

77 (64.2)

Age, mean ± SD (years)

56.1 ± 11.8

Weight, mean ± SD (kg)

77.8 ± 17.0

Hematology

Hb, mean ± SD (g/dl)

11.1 ± 2.8

Leukocytes, mean ± SD (10³)

6.8 ± 4.1

Thrombocytes, mean ± SD (/nl)

134.5 ± 167.3

Biochemistry

AST, mean ± SD (U/l)

74.9 ± 116.5

ALT, mean ± SD (U/l)

55.1 ± 150.5

GGT, mean ± SD (U/l)

186.6 ± 209.6

AP, mean ± SD (U/l)

148.2 ± 82.0

Total bilirubin, mean ± SD (mg/dl)

3.6 ± 5.6

INR, mean ± SD

2.3 ± 8.2

CRP, mean ± SD (ng/ml)

2.3 ± 3.1

Albumin, mean ± SD (g/l)

3.2 ± 0.6

Creatinine, mean ± SD (mg/dl)

1.3 ± 0.9

Prognosis score

MELD, mean (range)

16.3 (6.2 to 35.6)

Liver-related complications

Ascites, n (%)

68 (56.7)

Hepatorenal syndrome, n (%)

26 (21.7)

Spontaneous bacterial peritonitis, n (%)

13 (10.8)

Hepatic encephalopathy, n (%)

25 (20.8)

Variceal bleeding, n (%)

10 (8.3)

Etiology of liver disease

Chronic hepatitis B, n (%)

10 (8.3)

Chronic hepatitis C, n (%)

34 (28.3)

Alcohol, n (%)

54 (45.0)

PSC, n (%)

4 (3.3)

PBC, n (%)

2 (1.7)

Autoimmune, n (%)

3 (2.5)

Hemochromatosis n (%)

2 (1.7)

NASH, n (%)

2 (1.7)

Toxic, n (%)

2 (1.7)

Alpha1 antitrypsin deficiency

1 (0.8)

Cryptogenic

6 (5.0)


Normal reference ranges for male and female patients, respectively, were 13.7 to 17.5 and 11.2 to 15.7 g/dl for hemoglobin (Hb), 4.0 to 10.4 and 4.2 to 9.07/nl for leukocytes, 163 to 337 and 182 to 369/nl for thrombocytes, 3.5 to 5.2 and 3.5 to 5.2 g/l for albumin. Upper limits of normal for male and female patients, respectively, were 40 and 35 U/l for aspartate aminotransferase (AST), 50 and 35 U/l for alanine aminotransferase (ALT), 60 and 40 U/l for gamma glutamyl transpeptidase (GGT), 130 and 105 U/l for alkaline phosphatase (AP), 1 and 1 mg/dl for total bilirubin, 0.5 and 0.5 ng/ml for C reactive protein (CRP), 1.25 and 1.09 mg/dl for creatinine. MELD, Model of end stage liver disease; PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis; SD, standard deviation.

Kronenberger et al. BMC Medicine 2012 10:102   doi:10.1186/1741-7015-10-102

Open Data