Figure 1.

A framework to elucidate pathogenic mechanisms from mutations to mental illness. The effects of mutations in different genes can be analyzed across development on diverse cell types, local circuit organization and emergent properties, functional connectivity on a macro scale and correlated behavior in animals or psychopathology in humans.

Mitchell et al. BMC Biology 2011 9:76   doi:10.1186/1741-7007-9-76
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