Additional file 3.
Glioblastoma spheroid-based migration on gelatin. Day 4 U-87 MG or KNS42 tumor spheroids were transferred onto a gelatin-coated 96-well flat-bottomed plate (a single spheroid per well) and tumor cell dissemination was monitored. Selected images from a time lapse study illustrate fast, dispersed migration for U-87 MG and a slower radial, collective migration for KNS42. Images were obtained by microscopy as described in methods section. Scale bar: 200 μm.
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Vinci et al. BMC Biology 2012 10:29 doi:10.1186/1741-7007-10-29