Figure 7.

Representative tissue microarray staining results illustrating YB-1 expression in relation to tumor stage (A and B) and progesterone receptor status (C and D). A and B: While YB-1 staining in small (pT1) tumors is predominantly cytoplasmic (A), large (pT4) tumors preferentially show a distinct condensation of YB-1 signal in the nuclei of tumor cells (B). C and D: In breast tumors with positive progesterone receptor status (C) YB-1 expression is predominantly cytoplasmic, while tumors that lost progesterone receptor expression (D) exhibit prominent nuclear YB-1 expression.