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28 result(s) for 'author#Edgar Dahl' within BMC

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  3. Posttranslational protein modifications are known to modulate key biological processes like proliferation and apoptosis. Accumulating evidence shows that ST6GAL1, an enzyme that catalyzes the transfer of siali...

    Authors: Pia Antony, Michael Rose, Axel Heidenreich, Ruth Knüchel, Nadine T Gaisa and Edgar Dahl
    Citation: BMC Cancer 2014 14:901
    Content type: Research article Published on:

  5. We have previously reported that expression of the Wnt antagonist genes SFRP1 and SFRP5 is frequently silenced by promoter hypermethylation in breast cancer. SFRP2 is a further Wnt inhibitor whose expression was ...

    Authors: Jürgen Veeck, Erik Noetzel, Nuran Bektas, Edgar Jost, Arndt Hartmann, Ruth Knüchel and Edgar Dahl
    Citation: Molecular Cancer 2008 7:83
    Content type: Research Published on:

  6. Expression of the putative Wnt signalling inhibitor Dickkopf-3 (DKK3) is frequently lost in human cancer tissues because of aberrant 5'-cytosine methylation within the DKK3 gene promoter. Since other Wnt signalli...

    Authors: Jürgen Veeck, Nuran Bektas, Arndt Hartmann, Glen Kristiansen, Uwe Heindrichs, Ruth Knüchel and Edgar Dahl
    Citation: Breast Cancer Research 2008 10:R82
    Content type: Research article Published on:

  7. The inter-alpha-trypsin inhibitors (ITI) are a family of plasma protease inhibitors, assembled from a light chain – bikunin, encoded by AMBP – and five homologous heavy chains (encoded by ITIH1, ITIH2, ITIH3, ITI...

    Authors: Alexander Hamm, Juergen Veeck, Nuran Bektas, Peter J Wild, Arndt Hartmann, Uwe Heindrichs, Glen Kristiansen, Tamra Werbowetski-Ogilvie, Rolando Del Maestro, Ruth Knuechel and Edgar Dahl
    Citation: BMC Cancer 2008 8:25
    Content type: Research article Published on:

  8. Epigenetic mechanisms such as DNA hypermethylation and modifications of histone amino acids are known to play an important role in the control of gene expression both in normal human development and tumorigene...

    Authors: Christoph Oing, Edgar Jost, Edgar Dahl, Stefan Wilop, Tim H. Brümmendorf and Oliver Galm
    Citation: Clinical Epigenetics 2011 2:43
    Content type: Original Article Published on:

  9. Cholangiocarcinoma (CCA) is the second most common primary liver cancer and associated with a dismal prognosis due to the lack of an efficient systemic therapy. In contrast to other cancers, new immunotherapie...

    Authors: Dong Liu, Lara Rosaline Heij, Zoltan Czigany, Edgar Dahl, Sven Arke Lang, Tom Florian Ulmer, Tom Luedde, Ulf Peter Neumann and Jan Bednarsch
    Citation: Journal of Experimental & Clinical Cancer Research 2022 41:127
    Content type: Review Published on:

  10. ISG15 is an ubiquitin-like molecule that is strongly upregulated by type I interferons as a primary response to diverse microbial and cellular stress stimuli. However, alterations in the ISG15 signalling pathway...

    Authors: Nuran Bektas, Erik Noetzel, Jürgen Veeck, Michael F Press, Glen Kristiansen, Amjad Naami, Arndt Hartmann, Arno Dimmler, Matthias W Beckmann, Ruth Knüchel, Peter A Fasching and Edgar Dahl
    Citation: Breast Cancer Research 2008 10:R58
    Content type: Research article Published on:

  11. The human gene ERH (Enhancer of the Rudimentary gene Homologue) has previously been identified by in silico analysis of four million ESTs as a gene differentially expressed in breast cancer. The biological functi...

    Authors: Menelaos Zafrakas, Inge Losen, Ruth Knüchel and Edgar Dahl
    Citation: BMC Cancer 2008 8:145
    Content type: Research article Published on:

  12. FOXM1 regulates expression of cell cycle related genes that are essential for progression into DNA replication and mitosis. Consistent with its role in proliferation, elevated expression of FOXM1 has been repo...

    Authors: Nuran Bektas, Anette ten Haaf, Jürgen Veeck, Peter Johannes Wild, Juliane Lüscher-Firzlaff, Arndt Hartmann, Ruth Knüchel and Edgar Dahl
    Citation: BMC Cancer 2008 8:42
    Content type: Research article Published on:

  13. Plasminogen activator inhibitor 1 (PAI-1) overexpression is an important prognostic and predictive biomarker in human breast cancer. SERBP1, a protein that is supposed to regulate the stability of PAI-1 mRNA, may...

    Authors: Nuran Bektas Serce, Andreas Boesl, Irina Klaman, Sonja von Serényi, Erik Noetzel, Michael F Press, Arno Dimmler, Arndt Hartmann, Jalid Sehouli, Ruth Knuechel, Matthias W Beckmann, Peter A Fasching and Edgar Dahl
    Citation: BMC Cancer 2012 12:597
    Content type: Research article Published on:

  14. The transcription factor GLI1, a member of the GLI subfamily of Krüppel-like zinc finger proteins is involved in signal transduction within the hedgehog pathway. Aberrant hedgehog signalling has been implicate...

    Authors: Anette ten Haaf, Nuran Bektas, Sonja von Serenyi, Inge Losen, Elfriede Christel Arweiler, Arndt Hartmann, Ruth Knüchel and Edgar Dahl
    Citation: BMC Cancer 2009 9:298
    Content type: Research article Published on:

  15. Mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2), two members of the secretoglobin superfamily, are known to be co-expressed in breast cancer, where their proteins form a covalent complex. Based on the relative...

    Authors: Menelaos Zafrakas, Beate Petschke, Andreas Donner, Florian Fritzsche, Glen Kristiansen, Ruth Knüchel and Edgar Dahl
    Citation: BMC Cancer 2006 6:88
    Content type: Research article Published on:

  16. Y-box binding protein-1 (YB-1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus YB-1 protein orchestrates transcription of proliferation-relat...

    Authors: Edgar Dahl, Abdelaziz En-Nia, Frank Wiesmann, Renate Krings, Sonja Djudjaj, Elisabeth Breuer, Thomas Fuchs, Peter J Wild, Arndt Hartmann, Sandra E Dunn and Peter R Mertens
    Citation: BMC Cancer 2009 9:410
    Content type: Research article Published on:

  17. Extracellular matrix (ECM) is known to maintain epithelial integrity. In carcinogenesis ECM degradation triggers metastasis by controlling migration and differentiation including cancer stem cell (CSC) charact...

    Authors: Michael Rose, Vera Kloten, Erik Noetzel, Lukas Gola, Josef Ehling, Timon Heide, Steffen K. Meurer, Aljona Gaiko-Shcherbak, Antonio S. Sechi, Sebastian Huth, Ralf Weiskirchen, Oliver Klaas, Wiebke Antonopoulos, Qiong Lin, Wolfgang Wagner, Jürgen Veeck…
    Citation: Molecular Cancer 2017 16:44
    Content type: Research Published on:

  18. The complex composition of different cell types within a tissue can be estimated by deconvolution of bulk gene expression profiles or with various single-cell sequencing approaches. Alternatively, DNA methylat...

    Authors: Marco Schmidt, Tiago Maié, Edgar Dahl, Ivan G. Costa and Wolfgang Wagner
    Citation: BMC Biology 2020 18:178
    Content type: Methodology article Published on:

  19. Endothelin (EDN) signalling plays a crucial role in cell differentiation, proliferation and migration processes. There is compelling evidence that altered EDN signalling is involved in carcinogenesis by modula...

    Authors: Frank Wiesmann, Jürgen Veeck, Oliver Galm, Arndt Hartmann, Manel Esteller, Ruth Knüchel and Edgar Dahl
    Citation: Breast Cancer Research 2009 11:R34
    Content type: Research article Published on:

  20. For early detection of breast cancer, the development of robust blood-based biomarkers that accurately reflect the host tumor is mandatory. We investigated DNA methylation in circulating free DNA (cfDNA) from ...

    Authors: Vera Kloten, Birte Becker, Kirsten Winner, Michael G Schrauder, Peter A Fasching, Tobias Anzeneder, Jürgen Veeck, Arndt Hartmann, Ruth Knüchel and Edgar Dahl
    Citation: Breast Cancer Research 2013 15:R4
    Content type: Research article Published on: