Table 2

Demographic, clinical and Doppler sonography characteristics in multiple sclerosis patients in the PREMiSe study
Phase 2 (n = 20)
Female gender, n (%) 14 (70)
Age in years, mean (SD) median 44.3 (9) 44.6
Age at onset in years, mean (SD) median 33.4 (10) 35.5
Disease duration in years, mean (SD) median 10.9 (7.1) 10
Disease course, n (%)
  RR 13 (65)
  RP 7 (35)
EDSS, mean (SD) median 3.9 (1.5) 3.8
Type of treatment, n (%)
  Interferon beta 15 (75)
  Glatiramer acetate 4 (20)
  Combination 0 (0)
  Others 1 (5)
VH CCSVI criterion, n (%)
  VH1 8 (40)
  VH2 19 (95)
  VH3 20 (100)
  VH4 14 (70)
  VH5 4 (20)
≥2 CCSVI criteria*, n (%) 20 (100)
≥2 CCSVI extracranial criteria, n (%) 20 (100)

Legend: PREMiSe - Prospective Randomized Endovascular therapy in Multiple Sclerosis (study); RR - relapsing-remitting; RP - relapsing-progressive; EDSS - Expanded Disability Status Scale; VH – venous hemodynamic; CCSVI -chronic cerebrospinal venous insufficiency; SD - standard deviation.

*The overall CCSVI criteria report both the extracranial and intracranial assessments on DS.

Zivadinov et al.

Zivadinov et al. BMC Neurology 2013 13:151   doi:10.1186/1471-2377-13-151

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