Table 8

Diagnostic performance of the 4DSQ and HADS anxiety scales with respect to detecting panic disorder, agoraphobia and social phobia (prevalence 19%)*

4DSQ anxiety

sensitivity

specificity

PPV

NPV


≥4

0.98

0.53

0.33

0.99


≥5

0.89

0.61

0.35

0.96


≥6

0.86

0.68

0.39

0.95


≥7

0.82

0.73

0.42

0.95


≥8

0.79

0.78

0.46

0.94


≥9

0.71

0.82

0.49

0.92


≥10

0.64

0.85

0.49

0.91


≥11

0.54

0.89

0.53

0.89


≥12

0.43

0.91

0.53

0.87


≥13

0.32

0.93

0.50

0.85


≥14

0.27

0.94

0.50

0.85


≥15

0.23

0.96

0.56

0.84


HADS anxiety


≥8

1.00

0.23

0.23

1.00


≥9

1.00

0.29

0.25

1.00


≥10

0.95

0.38

0.26

0.97


≥11

0.86

0.45

0.27

0.93


≥12

0.80

0.56

0.30

0.92


≥13

0.68

0.65

0.31

0.90


≥14

0.63

0.73

0.35

0.89


≥15

0.57

0.80

0.40

0.89


≥16

0.41

0.87

0.43

0.86


≥17

0.27

0.92

0.44

0.84


≥18

0.20

0.96

0.52

0.84


* For each scale three cut-off points are highlighted in bold type: the optimal cut-off point with the best balance between sensitivity and specificity, the best lower cut-off point with a sensitivity ≥0.85, and the best higher cut-off point with a specificity ≥0.85

4DSQ = Four-Dimensional Symptom Questionnaire

HADS = Hospital Anxiety and Depression Scale

PPV = positive predictive value

NPV = negative predictive value

Terluin et al. BMC Family Practice 2009 10:58   doi:10.1186/1471-2296-10-58

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