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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Molecular Biology 2009, 10 :55
RNF168, a recently identified RING finger protein, exhibits ubiquitin ligase activity which targets the H2A family of histones, and on genotoxic insult, colocalizes with H2AX at dsDNA breaks, activating prolonged ubiquitination and amplifying the DNA damage response.
BMC Molecular Biology 2009, 10 :51
Muscle-specific modifications of histones H3 and H4 within the Desmin gene cluster and its 5' locus control region correlate with different patterns of DNA methylation and gene expression in human myoblasts and myotubes but not blood cells.
BMC Molecular Biology 2009, 10 :38
Dicer and TAR RNA binding protein (TRBP), components of the human RNA-induced silencing complex (RISC), interact via specific domains and deletion of one of the domains, C4 of TRBP, prevents colocalization and RNA interference.
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Methodology article
High quality RNA from multiple brain regions simultaneously acquired by laser capture microdissection Wei-Zhi Wang, Franziska M Oeschger, Sheena Lee, Zoltan Molnar BMC Molecular Biology 2009, 10 :69 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Expression of HNF4alpha in the human and rat choroid plexus - Implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier Monika Niehof, Juergen Borlak BMC Molecular Biology 2009, 10 :68 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Cooperation between NRF-2 and YY-1 transcription factors is essential for triggering the expression of the PREPL-C2ORF34 bidirectional gene pair Chien-Chang Huang, Wun-Shaing W Chang BMC Molecular Biology 2009, 10 :67 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of valid reference genes during the differentiation of human myoblasts Jens Stern-Straeter, Gabriel A Bonaterra, Karl Hormann, Ralf Kinscherf, Ulrich R Goessler BMC Molecular Biology 2009, 10 :66 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies Philippos A Papathanos, Nikolai Windbichler, Miriam Menichelli, Austin Burt, Andrea Crisanti BMC Molecular Biology 2009, 10 :65 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of a novel nucleolin related protein (NRP) gene expressed during rat spermatogenesis
Keerthi T Chathoth, Gayatri Ganesan, M RS Rao BMC Molecular Biology 2009, 10 :64 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Selection and evaluation of reference genes for improved interrogation of microbial transcriptomes: case study with the extremophile Acidithiobacillus ferrooxidans. Pamela A Nieto, Paulo C Covarrubias, Eugenia Jedlicki, David S Holmes, Raquel Quatrini BMC Molecular Biology 2009, 10 :63 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Construction of an adult barnacle (Balanus amphitrite) cDNA library and selection of reference genes for quantitative RT-PCR studies Tristano Bacchetti De Gregoris, Marco Borra, Elio Biffali, Thomas Bekel, J GRANT Burgess, Richard R Kirby, Anthony S Clare BMC Molecular Biology 2009, 10 :62 (24 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
A strategy for enrichment of claudins based on their affinity to Clostridium perfringens enterotoxin Dorte Lohrberg, Eberhard Krause, Michael Schumann, Jorg Piontek, Lars Winkler, Ingolf E Blasig, Reiner F Haseloff BMC Molecular Biology 2009, 10 :61 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Elongation factor eEF1B modulates functions of the release factors eRF1 and eRF3 and the efficiency of translation termination in yeast Igor A Valouev, Gleb V Fominov, Elizaveta E Sokolova, Vladimir N Smirnov, Michael D Ter-Avanesyan BMC Molecular Biology 2009, 10 :60 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Stable nuclear transformation of Gonium pectorale Kai Lerche, Armin Hallmann BMC Biotechnology 2009, 9 :64 (10 [Abstract ] [Provisional PDF ]
Research article
Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes Katsunori Fujiki, Fumi Kano, Kunio Shiota, Masayuki Murata BMC Biology 2009, 7 :38 (10 [Abstract ] [Provisional PDF ]
Review
Molecular fingerprinting of radiation resistant tumors: Can we apprehend and rehabilitate the suspects? Charles J. Rosser, Micah Gaar, Stacy Porvasnik BMC Cancer 2009, 9 :225 (9 [Abstract ] [Provisional PDF ]
Software
puma: a Bioconductor package for Propagating Uncertainty in Microarray Analysis Richard D Pearson, Xuejun Liu, Guido Sanguinetti, Marta Milo, Neil D Lawrence, Magnus Rattray BMC Bioinformatics 2009, 10 :211 (9 [Abstract ] [Provisional PDF ]
Research
Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome Elizabeth A Rach, Hsiang-Yu Yuan, William H Majoros, Pavel Tomancak, Uwe Ohler Genome Biology 2009, 10 :R73 (9 [Abstract ] [Provisional PDF ]
Research article
Stem cell and epithelial-mesenchymal transition markers are frequently over-expressed in circulating tumor cells of metastatic breast cancer patients Bahriye Aktas, Mitra Tewes, Tanja Fehm, Siegfried Hauch, Rainer Kimmig, Sabine Kasimir-Bauer Breast Cancer Research 2009, 11 :R46 (9 [Abstract ] [Provisional PDF ]
Research article
Domain swapping reveals that the N-terminal domain of the sensor kinase KdpD in Escherichia coli is important for signaling Ralf Heermann, Marie-Luise Lippert, Kirsten Jung BMC Microbiology 2009, 9 :133 (9 [Abstract ] [Provisional PDF ]
Research article
Integrin alpha6B beta4 inhibits colon cancer cell proliferation and c-Myc activity Anders BONDO Dydensborg, Inga C Teller, Jean-Francois Groulx, Nuria Basora, Frederic Pare, Elizabeth Herring, Remy Gauthier, Dominique Jean, Jean-Francois Beaulieu BMC Cancer 2009, 9 :223 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Genome-wide analysis of interactions between ATP-dependent chromatin remodeling and histone modifications Zhiming Dai, Xianhua Dai, Qian Xiang, Jihua Feng, Jiang Wang, Yangyang Deng, Caisheng He BMC Genomics 2009, 10 :304 (8 [Abstract ] [Provisional PDF ]
Short report
Improvement of a real-time RT-PCR assay for the detection of enterovirus RNA Marian A.C. Piqueur, Walter A. Verstrepen, Peggy Bruynseels, An H. Mertens Virology Journal 2009, 6 :95 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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