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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
BMC Molecular Biology 2009, 10 :103
A putative regulatory sequence has been characterized within exon 6A of the vascular endothelial growth factor (VEGF) mRNA, which is involved in alternative splicing of this exon and regulates the expression levels of the isoforms of VEGF.
BMC Molecular Biology 2009, 10 :101
The hypoxia-tolerant grass carp has two CITED3 genes whose promoters bind HIF-1 as they are induced by hypoxia in the liver and kidneys, and whose products are co-transcriptional regulators that interact with p300 and affect HIF-1 activity.
BMC Molecular Biology 2009, 10 :89
Monomers of the transcriptional regulator C-terminal binding protein 2 (CtBP2) bind competitively to the PLDLS-motif cofactor zinc-finger E-box binding homeobox (ZEB) and the histone deacetylase HDAC2, but do not mediate transcriptional repression, while dimers which bind both are functional.
Latest articles published in BMC Molecular Biology [more info ]
Research article
Selective control of primer usage in multiplex one-step reverse transcription PCR Elena Hidalgo Ashrafi, Joyclyn Yee, Natasha Paul BMC Molecular Biology 2009, 10 :113 (30 December 2009) [Abstract ] [Provisional PDF ]
Research article
Selection of reference genes for quantitative RT-PCR studies in Rhipicephalus (Boophilus) microplus and Rhipicephalus appendiculatus ticks and determination of the expression profile of Bm86 Ard M Nijhof, Jesper A Balk, Milagros Postigo, Frans Jongejan BMC Molecular Biology 2009, 10 :112 (29 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Innovative approach for transcriptomic analysis of obligate intracellular pathogen: selective capture of transcribed sequences of Ehrlichia ruminantium Loic Emboule, France Daigle, Damien F Meyer, Bernard Mari, Valerie Pinarello, Christian Sheikboudou, Virginie Magnone, Roger Frutos, Alain Viari, Pascal Barbry, Dominique Martinez, Thierry Lefrancois, Nathalie Vachiery BMC Molecular Biology 2009, 10 :111 (24 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1 Caroline Canfield, Justin Rains, Arrigo De Benedetti BMC Molecular Biology 2009, 10 :110 (20 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Characterization of the transcripts and protein isoforms for cytoplasmic polyadenylation element binding protein-3 (CPEB3) in the mouse retina Xiang-Ping Wang, Nigel G.F. Cooper BMC Molecular Biology 2009, 10 :109 (14 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Transpositionally active episomal hAT elements. David A. O'Brochta, Christina D. Stosic, Kristina Pilitt, Ramanand A. Subramanian, Robert H. Hice, Peter W. Atkinson BMC Molecular Biology 2009, 10 :108 (14 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Nuclear factor I-A represses expression of the cell adhesion molecule L1 Tanja Schneegans, Uwe Borgmeyer, Moritz Hentschke, Richard M Gronostajski, Melitta Schachner, Thomas Tilling BMC Molecular Biology 2009, 10 :107 (14 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Quantitative TaqMan(R) real-time PCR assays for gene expression normalisation in feline tissues Yvonne Kessler, A. KATRIN Helfer-Hungerbuehler, Valentino Cattori, Marina L. Meli, Bigna Zellweger, Pete Ossent, Barbara Riond, Claudia E. Reusch, Hans Lutz, Regina Hofmann-Lehmann BMC Molecular Biology 2009, 10 :106 (11 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Sequence-dependent DNA helical rise and nucleosome stability Francesco Pedone, Daniele Santoni BMC Molecular Biology 2009, 10 :105 (27 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Arsenic transport by zebrafish aquaglyceroporins Mohamad Hamdi, Marco A Sanchez, Lauren C Beene, Qianyong Liu, Scott M Landfear, Barry P Rosen, Zijuan Liu BMC Molecular Biology 2009, 10 :104 (25 November 2009) [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Function of nuclear transport factor 2 and Ran in the 20E signal transduction pathway in the cotton bollworm, Helicoverpa armigera Hong-Juan He, Qian Wang, Wei-Wei Zheng, Jin-Xing Wang, Qi-Sheng Song, Xiao-Fan Zhao BMC Cell Biology 2010, 11 :1 (2 January 2010) [Abstract ] [Provisional PDF ]
Research
Regulation of Akt(ser473)phosphorylation by Choline kinase in breast carcinoma cells Boon Tin Chua, David Gallego-Ortega, Ana Ramirez de Molina, Axel Ullrich, Juan Carlos Lacal, Julian Downward Molecular Cancer 2009, 8 :131 (31 December 2009) [Abstract ] [Provisional PDF ]
Research article
Virus infection elevates transcriptional activity of miR164a promoter in plants Ariel A Bazzini, Natalia I Almasia, Carlos A Manacorda, Vanesa C Mongelli, Gabriela Conti, Guillermo A Maroniche, Maria C Rodriguez, Ana J Distefano, H E Hopp, Mariana del Vas, Sebastian Asurmendi BMC Plant Biology 2009, 9 :152 (30 December 2009) [Abstract ] [Provisional PDF ]
Research
Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma Tao Wang, Hongli Liu, Yeshan Chen, Wei Liu, Jing Yu, Gang Wu Journal of Experimental & Clinical Cancer Research 2009, 28 :160 (30 December 2009) [Abstract ] [Provisional PDF ]
Research article
Polymorphism in the flanking regions of the PbGP43 gene from the human pathogen Paracoccidioides brasiliensis: search for protein binding sequences and poly(A) cleavage sites Antonio A Rocha, Flavia V Morais, Rosana Puccia BMC Microbiology 2009, 9 :277 (30 December 2009) [Abstract ] [Provisional PDF ]
Research
Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine Xiaoping Gu, Xiaoli Wu, Yue Liu, Songqin Cui, Zhengliang Ma Molecular Pain 2009, 5 :76 (30 December 2009) [Abstract ] [Provisional PDF ]
Research article
The powdery mildew resistance gene REN1 co-segregates with an NBS-LRR gene cluster in two Central Asian grapevines Courtney Coleman, Dario Copetti, Guido Cipriani, Sarolta Hoffmann, Pal Kozma, Laszlo Kovacs, Michele Morgante, Raffaele Testolin, Gabriele Di Gaspero BMC Genetics 2009, 10 :89 (30 December 2009) [Abstract ] [Provisional PDF ]
Methodology
Impact of ubiquitous inhibitors on the GUS gene reporter system: evidence from the model plants Arabidopsis, tobacco and rice and correction methods for quantitative assays of transgenic and endogenous GUS Simone Fior, Paolo D Gerola Plant Methods 2009, 5 :19 (30 December 2009) [Abstract ] [Provisional PDF ]
Research article
HIV-1 subtype and viral tropism determination for evaluating antiretroviral therapy options: an analysis of archived Kenyan blood samples Raphael W Lihana, Samoel A Khamadi, Raphael M Lwembe, Joyceline G Kinyua, Joseph K Muriuki, Nancy J Lagat, Fredrick A Okoth, Ernest P Makokha, Elijah M Songok BMC Infectious Diseases 2009, 9 :215 (30 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Tuning microbial hosts for membrane protein production Maria Freigassner, Harald Pichler, Anton Glieder Microbial Cell Factories 2009, 8 :69 (29 December 2009) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]