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BMC Molecular Biology

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
J. Ann Le Good PhD


Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function. BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.



BMC Featured articles

wikipedia
BMC Molecular Biology 2009, 10:103
A putative regulatory sequence has been characterized within exon 6A of the vascular endothelial growth factor (VEGF) mRNA, which is involved in alternative splicing of this exon and regulates the expression levels of the isoforms of VEGF.
http://fl.biology.usgs.gov/pics/nonindig_fish/nonindig_fish.html
BMC Molecular Biology 2009, 10:101
The hypoxia-tolerant grass carp has two CITED3 genes whose promoters bind HIF-1 as they are induced by hypoxia in the liver and kidneys, and whose products are co-transcriptional regulators that interact with p300 and affect HIF-1 activity.
Image credit: Wikipedia CtBP2
BMC Molecular Biology 2009, 10:89
Monomers of the transcriptional regulator C-terminal binding protein 2 (CtBP2) bind competitively to the PLDLS-motif cofactor zinc-finger E-box binding homeobox (ZEB) and the histone deacetylase HDAC2, but do not mediate transcriptional repression, while dimers which bind both are functional.


BMC  Latest articles published in BMC Molecular Biology        [more info]


Research article
Selective control of primer usage in multiplex one-step reverse transcription PCR
Elena Hidalgo Ashrafi, Joyclyn Yee, Natasha Paul
BMC Molecular Biology 2009, 10:113 (30December2009)
[Abstract] [Provisional PDF]

Research article
Selection of reference genes for quantitative RT-PCR studies in Rhipicephalus (Boophilus) microplus and Rhipicephalus appendiculatus ticks and determination of the expression profile of Bm86
Ard M Nijhof, Jesper A Balk, Milagros Postigo, Frans Jongejan
BMC Molecular Biology 2009, 10:112 (29December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Methodology article
Innovative approach for transcriptomic analysis of obligate intracellular pathogen: selective capture of transcribed sequences of Ehrlichia ruminantium
Loic Emboule, France Daigle, Damien F Meyer, Bernard Mari, Valerie Pinarello, Christian Sheikboudou, Virginie Magnone, Roger Frutos, Alain Viari, Pascal Barbry, Dominique Martinez, Thierry Lefrancois, Nathalie Vachiery
BMC Molecular Biology 2009, 10:111 (24December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1
Caroline Canfield, Justin Rains, Arrigo De Benedetti
BMC Molecular Biology 2009, 10:110 (20December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Characterization of the transcripts and protein isoforms for cytoplasmic polyadenylation element binding protein-3 (CPEB3) in the mouse retina
Xiang-Ping Wang, Nigel G.F. Cooper
BMC Molecular Biology 2009, 10:109 (14December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Transpositionally active episomal hAT elements.
David A. O'Brochta, Christina D. Stosic, Kristina Pilitt, Ramanand A. Subramanian, Robert H. Hice, Peter W. Atkinson
BMC Molecular Biology 2009, 10:108 (14December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Nuclear factor I-A represses expression of the cell adhesion molecule L1
Tanja Schneegans, Uwe Borgmeyer, Moritz Hentschke, Richard M Gronostajski, Melitta Schachner, Thomas Tilling
BMC Molecular Biology 2009, 10:107 (14December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Quantitative TaqMan(R) real-time PCR assays for gene expression normalisation in feline tissues
Yvonne Kessler, A. KATRIN Helfer-Hungerbuehler, Valentino Cattori, Marina L. Meli, Bigna Zellweger, Pete Ossent, Barbara Riond, Claudia E. Reusch, Hans Lutz, Regina Hofmann-Lehmann
BMC Molecular Biology 2009, 10:106 (11December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Sequence-dependent DNA helical rise and nucleosome stability
Francesco Pedone, Daniele Santoni
BMC Molecular Biology 2009, 10:105 (27November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Arsenic transport by zebrafish aquaglyceroporins
Mohamad Hamdi, Marco A Sanchez, Lauren C Beene, Qianyong Liu, Scott M Landfear, Barry P Rosen, Zijuan Liu
BMC Molecular Biology 2009, 10:104 (25November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Function of nuclear transport factor 2 and Ran in the 20E signal transduction pathway in the cotton bollworm, Helicoverpa armigera
Hong-Juan He, Qian Wang, Wei-Wei Zheng, Jin-Xing Wang, Qi-Sheng Song, Xiao-Fan Zhao
BMC Cell Biology 2010, 11:1 (2January2010)
[Abstract] [Provisional PDF]

Research
Regulation of Akt(ser473)phosphorylation by Choline kinase in breast carcinoma cells
Boon Tin Chua, David Gallego-Ortega, Ana Ramirez de Molina, Axel Ullrich, Juan Carlos Lacal, Julian Downward
Molecular Cancer 2009, 8:131 (31December2009)
[Abstract] [Provisional PDF]

Research article
Virus infection elevates transcriptional activity of miR164a promoter in plants
Ariel A Bazzini, Natalia I Almasia, Carlos A Manacorda, Vanesa C Mongelli, Gabriela Conti, Guillermo A Maroniche, Maria C Rodriguez, Ana J Distefano, H E Hopp, Mariana del Vas, Sebastian Asurmendi
BMC Plant Biology 2009, 9:152 (30December2009)
[Abstract] [Provisional PDF]

Research
Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma
Tao Wang, Hongli Liu, Yeshan Chen, Wei Liu, Jing Yu, Gang Wu
Journal of Experimental & Clinical Cancer Research 2009, 28:160 (30December2009)
[Abstract] [Provisional PDF]

Research article
Polymorphism in the flanking regions of the PbGP43 gene from the human pathogen Paracoccidioides brasiliensis: search for protein binding sequences and poly(A) cleavage sites
Antonio A Rocha, Flavia V Morais, Rosana Puccia
BMC Microbiology 2009, 9:277 (30December2009)
[Abstract] [Provisional PDF]

Research
Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine
Xiaoping Gu, Xiaoli Wu, Yue Liu, Songqin Cui, Zhengliang Ma
Molecular Pain 2009, 5:76 (30December2009)
[Abstract] [Provisional PDF]

Research article
The powdery mildew resistance gene REN1 co-segregates with an NBS-LRR gene cluster in two Central Asian grapevines
Courtney Coleman, Dario Copetti, Guido Cipriani, Sarolta Hoffmann, Pal Kozma, Laszlo Kovacs, Michele Morgante, Raffaele Testolin, Gabriele Di Gaspero
BMC Genetics 2009, 10:89 (30December2009)
[Abstract] [Provisional PDF]

Methodology
Impact of ubiquitous inhibitors on the GUS gene reporter system: evidence from the model plants Arabidopsis, tobacco and rice and correction methods for quantitative assays of transgenic and endogenous GUS
Simone Fior, Paolo D Gerola
Plant Methods 2009, 5:19 (30December2009)
[Abstract] [Provisional PDF]

Research article
HIV-1 subtype and viral tropism determination for evaluating antiretroviral therapy options: an analysis of archived Kenyan blood samples
Raphael W Lihana, Samoel A Khamadi, Raphael M Lwembe, Joyceline G Kinyua, Joseph K Muriuki, Nancy J Lagat, Fredrick A Okoth, Ernest P Makokha, Elijah M Songok
BMC Infectious Diseases 2009, 9:215 (30December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Review
Tuning microbial hosts for membrane protein production
Maria Freigassner, Harald Pichler, Anton Glieder
Microbial Cell Factories 2009, 8:69 (29December2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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