Length distribution of the paired-end sequenced fragments. Distribution from chromosome 21 of the sample "before treatment", discussed in Section "Real data". The length values have been extracted from the mapped paired-ends, where only unambiguously and exactly aligned pairs have been considered. Strictly speaking, also discordant mappings (those, spanning insertions or deletions) are contained. But due to their low abundance, they do not affect the distribution Significantly.
Wittler BMC Genomics 2013 14(Suppl 1):S12 doi:10.1186/1471-2164-14-S1-S12