The mutation rates for methylated CpG sites in the human genome and categorized genomic regions. The X-axis includes CpG sites with different methylation levels (H_mCpG: highly methylated CpG (> 80%); HI_mCpG: high-intermediately methylated CpG (60-80%); I_mCpG: intermediately methylated CpG (40-60%); LI_mCpG: low-intermediately methylated CpG (20-40%); L_mCpG: lowly methylated CpG (≤ 20%)). The Y-axis is the mutation rate that was calculated as the density of SNPs at CpG sites.
Xia et al. BMC Genomics 2012 13(Suppl 8):S7 doi:10.1186/1471-2164-13-S8-S7