Table 8

Mouse phenotypes significantly associated with top candidate genes by ToppFun.

Phenotype ID

Phenotype name

p-value

Terms in query

Terms in genome


MP:0009745

Abnormal behavioral response to xenobiotic

6.77 × 10-7

12

215

MP:0002206

Abnormal CNS synaptic transmission

4.31 × 10-6

14

382

MP:0003635

Abnormal synaptic transmission

3.57 × 10-5

14

450

MP:0002062

Abnormal conditioning behavior

6.87 × 10-5

10

199

MP:0002063

Abnormal learning/memory/conditioning

9.26 × 10-5

13

405

MP:0002065

Abnormal fear/anxiety-related behavior

1.05 × 10-4

10

208

MP:0001362

Abnormal anxiety-related response

3.59 × 10-4

9

179

MP:0002572

Abnormal emotion/affect behavior

8.34 × 10-4

11

329

MP:0001454

Abnormal cued conditioning behavior

1.41 × 10-3

6

66

MP:0003633

Abnormal nervous system physiology

2.44 × 10-3

20

1333

MP:0001399

Hyperactivity

2.57 × 10-3

9

226

MP:0001363

Increased anxiety-related response

2.86 × 10-3

7

117

MP:0009357

Abnormal seizure response to inducing agent

9.04 × 10-3

7

139

MP:0001449

Abnormal learning/memory

1.22 × 10-2

10

349

MP:0003088

Abnormal prepulse inhibition

1.45 × 10-2

5

57

MP:0003313

Abnormal locomotor activation

1.46 × 10-2

13

630

MP:0000950

abnormal seizure response to pharmacological agent

1.53 × 10-2

6

99

MP:0002945

Abnormal inhibitory postsynaptic currents

1.58 × 10-2

5

58

MP:0004008

Abnormal GABA-mediated receptor currents

2.85 × 10-2

3

11

MP:0009747

Impaired behavioral response to xenobiotic

3.45 × 10-2

5

68

MP:0004747

Abnormal cochlear OHC afferent innervation pattern

3.48 × 10-2

2

2


Zhao et al. BMC Genomics 2012 13(Suppl 8):S16   doi:10.1186/1471-2164-13-S8-S16

Open Data