Table 2

Sensitivity and specificity

Variable and cut-off value

Sensitivity (%)

Specificity (%)


Number of bp between SNPs

0

97.8

100

10

97.2

99.99988

25

96.6

99.99975

50

95.8

99.99959

75

94.6

99.99935

100

93.8

99.99918


Number of bp from a sequence end


0

97.8

100

10

97.8

100

25

97.8

100

50

97.8

100

75

97.8

100

100

97.7

100


Evaluation of sensitivity (SN) and specificity (SP) using different settings of minimum number of bp between SNPs (prune) and minimum number of bp from a sequence end (e) for SNP detection on a simulated dataset consisting of a genome of 4,878,012 bp with 1,000 randomly SNP artificial inserted.

Leekitcharoenphon et al. BMC Genomics 2012 13(Suppl 7):S6   doi:10.1186/1471-2164-13-S7-S6

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