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This article is part of the supplement: Eleventh International Conference on Bioinformatics (InCoB2012): Computational Biology

Open Access Proceedings

Comparison and evaluation of pathway-level aggregation methods of gene expression data

Seungwoo Hwang

Author Affiliations

Korean Bioinformation Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea

BMC Genomics 2012, 13(Suppl 7):S26  doi:10.1186/1471-2164-13-S7-S26

Published: 13 December 2012

Additional files

Additional File 1:

Supplementary Methods. This document contains the schematic and mathematical description of the pathway-level aggregation methods.

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Additional File 2:

Relationship between size and rank of pathways. The 163 pathways, whose sizes are between 20 and 300, are ranked by Student's t-test p-value in all fourteen datasets. Smaller ranks correspond to more significance. For each rank, a box plot was prepared to summarize the sizes of the pathways at that rank in the fourteen datasets. Median sizes are joined by thick line to show the overall size-rank trend.

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Open Data