The Receiver Operating Characteristic (ROC) curves for simulation datasets of hybrid models. The ROC curves are displayed for five independent interacting SNP pairs.The MAF and heritability parameters were varied (A) h2=0.1, MAF = 0.2, (B) h2=0.2, MAF = 0.2, (C) h2=0.3, MAF = 0.2, (D) h2=0.4, MAF = 0.2, (E) h2=0.2, MAF = 0.4, (F) h2=0.1, MAF = 0.4. The ρdiffvalues are shown that give the maximum true positive rate with the lowest false positive rate (red dots).
Piriyapongsa et al. BMC Genomics 2012 13(Suppl 7):S2 doi:10.1186/1471-2164-13-S7-S2