Additional file 15.

Amino acid composition of SMAT80 predicted apicomplexan kinases and proteases compared to yeast kinases and proteases. The SMAT80 predicted apicomplexan kinases and proteases significantly differ from yeast kinases and proteases respectively in terms of non-polar and negatively charged amino acids content. We think this was one of the reasons that standard BLOSUM matrices could not detect orthologs for these proteins against SwissProt database.

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Ali et al. BMC Genomics 2012 13(Suppl 7):S19   doi:10.1186/1471-2164-13-S7-S19