Additional file 1.
SMAT80 gives poor E-values for coccidian specific proteins in non-coccidian parasites. BLAST searches for coccidian-specific oocyst wall proteins of Cryptosporidium parvum were carried out against the hematozoans (non-coccidian) and coccidian apicomplexan parasites using BLOSUM62 and SMAT80 matrices. SMAT80 correctly gave poor E-values and/or bit scores for BLAST hits of these coccidian-specific proteins in hematozoans.
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Ali et al. BMC Genomics 2012 13(Suppl 7):S19 doi:10.1186/1471-2164-13-S7-S19