This article is part of the supplement: Proceedings of the 6th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-meeting 2010)

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Preimplantation development regulatory pathway construction through a text-mining approach

Elisa Donnard12, Adriano Barbosa-Silva34, Rafael LM Guedes1, Gabriel R Fernandes1, Henrique Velloso1, Matthew J Kohn5, Miguel A Andrade-Navarro3 and J Miguel Ortega1*

Author Affiliations

1 Laboratório Biodados, Dept. de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte - MG, Brazil

2 Departamento de Bioquímica, Universidade de São Paulo - SP, Brazil

3 Computational Biology and Data Mining Group, Max-Delbrück Center for Molecular Medicine, Robert-Rössle-Strasse 10, D-13125, Berlin, Germany

4 Bioinformatics Graduate Program, Federal University of Paraná - UFPR (SEPT). Rua Dr. Alcides Vieira Arcoverde 1225, CEP 81520-260. Curitiba-PR, Brazil

5 New York State Stem Cell Science, New York State Department of Health Wadsworth Center, Rm C345, New York, USA

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BMC Genomics 2011, 12(Suppl 4):S3  doi:10.1186/1471-2164-12-S4-S3

Published: 22 December 2011

Additional files

Additional file 1:

Homolog clusters. Clusters of homologous sequences found by SeedServer for each of the genes in the preimplantation pathway. For each gene, the left column shows the clustered sequence Uniprot ID and the right column shows the Taxonomy ID for this sequence.

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Additional file 2:

Ortholog functions in Drosophila melanogaster. This figure represents the corresponding D. melanogaster orthologs found by SeedServer and their respective interactions and functions in fruit fly development. Note that these orthologs are involved in processes related to D. melanogaster embryo development. See Additional file 3 for a table with gene name correspondence between the genes in this figure and the ones on Figure 3.

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Additional file 3:

Gene correspondence table. Human and Drosophila melanogaster gene name correspondence for the orthologs grouped by SeedServer. Column 3 lists the PubMed identifiers (PMIDs) from the papers where functions described in Additional file 2 were found.

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