Table 6

Percentage of PPIs in representative two-hybrid PPI datasets having coherent informative GO terms

CC

BP

MF

GO


S. cerevisiae Y2H PPI

49.74%

38.43%

35.90%

40.58%

S. cerevisiae random PPI

5.03%

3.70%

7.72%

7.08%

Info GO ratio of S. cerevisiae (Y2H PPI/ random)

9.88

10.38

4.65

5.73

Info GO term No.

57

173

78

365

C. jejuni Y2H PPI

47.37%

17.01%

16.27%

17.91%

C. jejuni random PPI

35.61%

11.04%

12.91%

13.97%

Info GO ratio of C. jejuni (Y2H PPI / random)

1.33

1.54

1.26

1.28

Info GO term No.

3

26

22

51

Synechocystis Y2H PPI

80.77%

26.16%

25.30%

29.47%

Synechocystis random PPI

44.94%

6.89%

8.59%

9.73%

Info GO ratio of Synechocystis (Y2H PPI / random)

1.80

3.79

2.95

3.03

Info GO term No.

3

30

30

63

M. tuberculosis B2H PPI

38.46%

14.36%

9.57%

13.83%

M. tuberculosis random PPI

38.30%

11.35%

8.35%

11.51%

Info GO ratio of M. tuberculosis (B2H PPI / random)

1.00

1.26

1.15

1.20

Info GO term No.

3

32

32

67


The table is a summary of the percentage of PPIs having coherent informative GO terms, number of informative GO terms and “Info GO ratio” in each of the representative two-hybrid PPI datasets in four organisms.

Info GO ratio = percentage of PPIs in two-hybrid PPI dataset having coherent informative GO terms / percentage of PPIs in random PPI dataset having coherent informative GO terms.

Zhou and Wong BMC Genomics 2011 12(Suppl 3):S20   doi:10.1186/1471-2164-12-S3-S20

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