Mapping of pTTSs and other regulatory elements on MYC gene region. Bottom plot shows detail map of pTTSs and maps other regulatory elements on MYC gene region and up plot shows zoomed region and regulatory sequences in the vicinity of start position of MYC gene. Red oval in the zoomed region: The uniquely mapped TTS (TTS15008128817597) located in the first exon of MYC gene is overlapped with the TFBS V$E2F_02 and with the CpG island. The next downstream TTS (TTS15008128817681) in the fist exon of MYC gene is also overlapped with other TFBS V$P300_01. However, for the last pTTS multiple locations in the human genome were found. Two G4 sequences (Quad-8-CCC-5773 and Quad-8-CC-5774) are also shown in a vicinity of start position of MYC gene One of this G4 (Quad-8-CCC-5773) is overlapped with pTTS TTS15008128817345 and include other pTTS TTS15008128817365.
Jenjaroenpun and Kuznetsov BMC Genomics 2009 10(Suppl 3):S9 doi:10.1186/1471-2164-10-S3-S9