simMC (≥ 8 kbp): semi-supervised setting. OFDEG+GC and tetranucleotide frequency (TF) comparison using semi-supervised methods, for the Phrap (A) and Arachne (B) assemblers. As anticipated, the addition of known seeds improves the accuracy of binning using OFDEG in a purely unsupervised manner. However, we note that at higher values of CP the classificaiton performance will degrade due to an increasing number of incorrect assignments made on ambiguous fragments.
Saeed and Halgamuge BMC Genomics 2009 10(Suppl 3):S10 doi:10.1186/1471-2164-10-S3-S10