simMC (≥ 10 reads): unsupervised setting. OFDEG, OFDEG+GC and tetranucleotide frequency (TF) comparison using unsupervised methods, for the Phrap (A) and Arachne (B) assemblers. Here we see a similar scenario to the 8 kbp tests. In this case, however, augmenting OFDEG with G-C content is much more beneficial, where OFDEG alone appears to offer lower accuracy.
Saeed and Halgamuge BMC Genomics 2009 10(Suppl 3):S10 doi:10.1186/1471-2164-10-S3-S10