Functional anthology of IDPs. More than 200,000 proteins and 710 SWISSPROT functional keywords each associated with at least 20 different proteins were analyzed [48-50]. Based on the bioinformatics analysis, 238 keywords were associated with the predicted intrinsic disorder. These keywords covered various functions and included almost all disease-related keywords. This is in a strict contrast to 302 keywords which were associated with the predicted order. Functionally, the vast majority of these keywords were various "ases". They contained almost no disease-related keywords.
Uversky et al. BMC Genomics 2009 10(Suppl 1):S7 doi:10.1186/1471-2164-10-S1-S7