Table 1

TRBV gene repertoires.

Subgroup

Number of genes identified in human TRB locus

Number of genes identified in bovine TRB locus

Number of bovine genes identified from cDNA analyses


Total

Functional

Total

Functional


1

1

2

1

1

3

1–2*

1

1

1

1

4

2–3*

2–3

2

2

2

5

8

5

4

1

1

6

8–9*

6–7 (+1)†

40

20

20

7

9

5 (+2)†

2

2

3

8

2

9

1

1

35

23

13

10

3

2 (+1)†

1

0

2

11

3

3

1

0

12

5

3

2

2

2

13

1

1

1

0

14

1

1

1

1

1

15

1

1

1

1

1

16

1

(+1)†

1

0

1

17

1

18

1

1

4

0

19

1

1

6

3

3

20

1

1

5

5

9

21

1

16

9

11

22

1

23

1

24

1

1

1

1

2

25

1

1

1

1

1

26

1

1

1

1

27

1

1

1

28

1

1

1

1

1

29

1

1

5

3

8

30

1

(+1) †

1

1

1

X

1

1

1


Total

64–67

40–42 (+6)

134

79

86


The total and functional repertoire of TRBV genes in the human TRB locus and in the third assembly of the bovine genome as well as the bovine TRBV gene repertoire identified from cDNA analysis. Details of the human repertoire are taken from the IMGT database http://imgt.cines.fr webcite. *denotes variation in germline repertoire due to insertion/deletion polymorphisms and † denotes TRBV genes which have alternative functional and non-functional alleles (TRBV6-2, TRBV7-3, TRBV7-4, TRBV10-1, TRBV16, TRBV30).

Connelley et al. BMC Genomics 2009 10:192   doi:10.1186/1471-2164-10-192

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