Neighbor-joining phylogenetic tree of the functional genomic repertoire of murine, human and bovine TRBJ genes. Analysis was completed on the coding and RS nucleotide sequence of functional TRBJ genes following complete deletion to remove gaps in the alignment. The final dataset included 59 positions. The 12 phylogenetic groups (1–12) have been indicated and the percentage bootstrap interior branch test value (PB) based on a 1000 replications is shown for each of the groups. Generally each group is composed of genes from the 3 species that share a conserved order in the genome; group 8 is unique in containing the orthologues of two adjacent genes human and murine TRBJ2-3 and TRBJ2-4 (and in the bovine TRBJ3-3 and TRBJ3-4 as well as TRBJ2-3).
Connelley et al. BMC Genomics 2009 10:192 doi:10.1186/1471-2164-10-192