Multiple sequence alignment of the proximal 350 bp of the promoter region showing conserved pockets bearing consensus recognition sequences for transcription factors (TFs). Regions conserved in at least 50% of the input sequence (4/8) that had putative TF binding sites were shown as boxed regions in the figure. Regions that are conserved across ancient boPAGs (PAG -2,-8,-11 and -12) were shaded in light grey and regions conserved across modern PAGs (PAG-3,-5,-15, and -18) were shaded in dark grey. Putative TFs capable of binding to the boxed residues were shown in the bottom of the alignment. The regions that are conserved across all the PAGs and the regions that are of importance for discussion were boxed (not shaded).
Telugu et al. BMC Genomics 2009 10:185 doi:10.1186/1471-2164-10-185