Figure 3.

Glycolysis pathway. In spite of the fragmentary nature of the composed meta-set, the Warburg effect is still reflected in the pathway map through increased abundance of lactate dehydrogenase (LDHB). Relative change and direction of change in transcript abundance of differentially expressed are marked with color flags. Red color designates higher and blue color designates lower transcript abundance compared to average between primary tumor (1) and metastatic samples (2). The legend for GeneGo pathway maps is given in Supplemental Figure 6 (Additional File 1).