BMC Bioinformatics

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This article is part of the supplement: Proceedings of the Fifth Annual MCBIOS Conference. Systems Biology: Bridging the Omics

Open Access Proceedings

From microarray to biology: an integrated experimental, statistical and in silico analysis of how the extracellular matrix modulates the phenotype of cancer cells

Mikhail G Dozmorov1*, Kimberly D Kyker1, Paul J Hauser1, Ricardo Saban4, David D Buethe1, Igor Dozmorov3, Michael B Centola4, Daniel J Culkin1 and Robert E Hurst1,2*

Author Affiliations

1 Department of Urology, Oklahoma University Health Sciences Centre, Oklahoma City, OK 73104, USA

2 Department of Biochemistry and Molecular Biology, Oklahoma University Health Sciences Centre, Oklahoma City, OK 73104, USA

3 Microarray Core Facility, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA

4 Department of Physiology, Oklahoma University Health Sciences Centre, Oklahoma City, OK 73104, USA

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BMC Bioinformatics 2008, 9(Suppl 9):S4 doi:10.1186/1471-2105-9-S9-S4

Published: 12 August 2008

Additional files

Additional file 1:

Supplemental Table S1. Activity of 345 transcription factors in cells grown on Matrigel and on Plastic. Values were obtained as described in Methods and are arbitrary units, but are normalized to protein content and exposure time against an assay standard of biotinylated DNA.

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