Table 3

Degrees of the source genes that are shared between the mutant network and the ChIP network (data for YPD medium only)

target genes

source gene

in the mutant network

in the ChIP network

shared between ChIP and mutant network

intersection significant according to hypergeometric test


YAL051W

YAF1

1

61

0

no

YOR028C

CIN5

1

153

0

no

YHL009C

YAP3

2

18

0

no

YKL043W

PHD1

3

67

0

no

YLR014C

PPR1

7

25

0

no

YBR083W

TEC1

20

42

0

no

YMR275C

BUL1

27

3

0

no

YPL049C

DIG1

32

51

0

no

YLR113W

HOG1

145

12

0

no

YOL067C

RTG1

177

6

0

no

YER040W

GLN3

52

16

1

no

YMR021C

MAC1

52

42

2

no

YGR040W

KSS1

253

18

2

no

YLR182W

SWI6

42

158

3

no

YOR038C

HIR2

25

16

2

yes

YMR042W

ARG80

5

16

4

yes

YDL056W

MBP1

6

134

4

yes

YMR019W

STB4

9

33

5

yes

YML007W

YAP1

37

72

8

yes

YDR146C

SWI5

35

120

9

yes

YHR084W

STE12

43

63

14

yes

YEL009C

GCN4

51

75

19

yes

YER111C

SWI4

547

161

29

yes


sum of edges

1572 (1157)

1362 (924)

102


13 source genes have common target genes in both networks (bold). Last column shows if the intersection between the target sets is larger than expected randomly (hypergeometric test, p < 0.05, 4000 genes in total)

Schlitt and Brazma BMC Bioinformatics 2007 8(Suppl 6):S9   doi:10.1186/1471-2105-8-S6-S9

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